N-Leucinyl Benzenesulfonamides as Structurally Simplified Leucyl-tRNA Synthetase Inhibitors

MH Charlton; R Aleksis; A Saint-Leger; Arya Gupta; E Loza; LR de Pouplana; I Kaula; D Gustina; M Madre; D Lola; K Jaudzems; G Edmund; CP Randall; L Kime; AJ O'Neill; Wil Goessens; A Jirgensons; PW Finn

doi:10.1021/acsmedchemlett.7b00374

N-Leucinyl Benzenesulfonamides as Structurally Simplified Leucyl-tRNA Synthetase Inhibitors

MH Charlton
, R Aleksis
, A Saint-Leger
, Arya Gupta
, E Loza
, LR de Pouplana
, I Kaula
, D Gustina
, M Madre
, D Lola
, K Jaudzems
, G Edmund
, CP Randall
, L Kime
, AJ O'Neill
, Wil Goessens
, A Jirgensons
, PW Finn

Medical Microbiology & Infectious Diseases

Research output: Contribution to journal › Article › Academic › peer-review

18 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	84-88
Number of pages	5
Journal	ACS Medicinal Chemistry Letters
Volume	9
Issue number	2
DOIs	https://doi.org/10.1021/acsmedchemlett.7b00374
Publication status	Published - 2018

Research programs

EMC MM-04-28-01

Access to Document

10.1021/acsmedchemlett.7b00374

http://hdl.handle.net/1765/104779

Cite this

Charlton, MH., Aleksis, R., Saint-Leger, A., Gupta, A., Loza, E., de Pouplana, LR., Kaula, I., Gustina, D., Madre, M., Lola, D., Jaudzems, K., Edmund, G., Randall, CP., Kime, L., O'Neill, AJ., Goessens, W., Jirgensons, A., & Finn, PW. (2018). N-Leucinyl Benzenesulfonamides as Structurally Simplified Leucyl-tRNA Synthetase Inhibitors. ACS Medicinal Chemistry Letters, 9(2), 84-88. https://doi.org/10.1021/acsmedchemlett.7b00374

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author = "MH Charlton and R Aleksis and A Saint-Leger and Arya Gupta and E Loza and \{de Pouplana\}, LR and I Kaula and D Gustina and M Madre and D Lola and K Jaudzems and G Edmund and CP Randall and L Kime and AJ O'Neill and Wil Goessens and A Jirgensons and PW Finn",

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doi = "10.1021/acsmedchemlett.7b00374",

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Charlton, MH, Aleksis, R, Saint-Leger, A, Gupta, A, Loza, E, de Pouplana, LR, Kaula, I, Gustina, D, Madre, M, Lola, D, Jaudzems, K, Edmund, G, Randall, CP, Kime, L, O'Neill, AJ, Goessens, W, Jirgensons, A & Finn, PW 2018, 'N-Leucinyl Benzenesulfonamides as Structurally Simplified Leucyl-tRNA Synthetase Inhibitors', ACS Medicinal Chemistry Letters, vol. 9, no. 2, pp. 84-88. https://doi.org/10.1021/acsmedchemlett.7b00374

TY - JOUR

T1 - N-Leucinyl Benzenesulfonamides as Structurally Simplified Leucyl-tRNA Synthetase Inhibitors

AU - Charlton, MH

AU - Aleksis, R

AU - Saint-Leger, A

AU - Gupta, Arya

AU - Loza, E

AU - de Pouplana, LR

AU - Kaula, I

AU - Gustina, D

AU - Madre, M

AU - Lola, D

AU - Jaudzems, K

AU - Edmund, G

AU - Randall, CP

AU - Kime, L

AU - O'Neill, AJ

AU - Goessens, Wil

AU - Jirgensons, A

AU - Finn, PW

PY - 2018

Y1 - 2018

U2 - 10.1021/acsmedchemlett.7b00374

DO - 10.1021/acsmedchemlett.7b00374

M3 - Article

C2 - 29456792

SN - 1948-5875

VL - 9

SP - 84

EP - 88

JO - ACS Medicinal Chemistry Letters

JF - ACS Medicinal Chemistry Letters

IS - 2

ER -