TY - JOUR
T1 - Neuro-Urology
T2 - Call for Universal, Resource-Independent Guidance
AU - Werneburg, Glenn T.
AU - Welk, Blayne
AU - Averbeck, Marcio A.
AU - Blok, Bertil F.M.
AU - Hamid, Rizwan
AU - Kennelly, Michael J.
AU - Liao, Limin
AU - Musco, Stefania
AU - Vasudeva, Pawan
AU - Kessler, Thomas M.
N1 - Funding Information:
This manuscript received no external funding.
Publisher Copyright:
© 2023 by the authors.
PY - 2023/1/29
Y1 - 2023/1/29
N2 - Neurogenic lower urinary tract dysfunction (NLUTD), the abnormal function of the lower urinary tract in the context of neurological pathology, has been the subject of multiple efforts worldwide for the development of clinical practice guidelines. These guidelines are based on the same body of evidence, and are therefore subject to the same gaps. For example, sexual and bowel dysfunction in the context of NLUTD, optimal renal function assessment in those who are non-ambulatory or with low muscle mass, optimal upper tract surveillance timing, and modification of diagnostic and treatment modalities for low-resource nations and communities are inadequately addressed. In addition, many aspects of the conclusions and final recommendations of the guidelines are similar. This duplicative work represents a large expenditure of time and effort, which we believe could be focused instead on evidence gaps. Here, we call for a global unified approach to create a single, resource-independent, comprehensive guidance on NLUTD, neurogenic sexual, and neurogenic bowel dysfunction. Targeted research addressing the evidence gaps should be called for and pursued. This will allow for focus to shift to filling the gaps in the evidence for future guidelines.
AB - Neurogenic lower urinary tract dysfunction (NLUTD), the abnormal function of the lower urinary tract in the context of neurological pathology, has been the subject of multiple efforts worldwide for the development of clinical practice guidelines. These guidelines are based on the same body of evidence, and are therefore subject to the same gaps. For example, sexual and bowel dysfunction in the context of NLUTD, optimal renal function assessment in those who are non-ambulatory or with low muscle mass, optimal upper tract surveillance timing, and modification of diagnostic and treatment modalities for low-resource nations and communities are inadequately addressed. In addition, many aspects of the conclusions and final recommendations of the guidelines are similar. This duplicative work represents a large expenditure of time and effort, which we believe could be focused instead on evidence gaps. Here, we call for a global unified approach to create a single, resource-independent, comprehensive guidance on NLUTD, neurogenic sexual, and neurogenic bowel dysfunction. Targeted research addressing the evidence gaps should be called for and pursued. This will allow for focus to shift to filling the gaps in the evidence for future guidelines.
UR - http://www.scopus.com/inward/record.url?scp=85148938731&partnerID=8YFLogxK
U2 - 10.3390/biomedicines11020397
DO - 10.3390/biomedicines11020397
M3 - Article
C2 - 36830934
AN - SCOPUS:85148938731
SN - 2227-9059
VL - 11
JO - Biomedicines
JF - Biomedicines
IS - 2
M1 - 397
ER -