Neurogenic tumours of the posterior mediastinum and differential diagnosis considerations

MA den Bakker*, A Weissferdt

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)
18 Downloads (Pure)


The mediastinal compartment harbours vital organs and structures, including the heart, great vessels, major airways, and thymus. These structures are embedded in and associated with soft-tissue elements consisting of adipose and fibro-collagenous tissue in which soft-tissue tumours may develop. A detailed inventory of soft-tissue tumours that may be encountered in the mediastinum based on the WHO 2013 classification was published in 2015. In addition, several comprehensive reviews on mediastinal soft-tissue pathology are available, including reviews focusing specifically on a single tumour type. This review will focus on primary neurogenic and spindle cell tumours of the somatic soft tissue of the posterior mediastinum and provide a discussion of the pertinent differential diagnoses.
Original languageEnglish
Pages (from-to)238-252
Number of pages15
Issue number1
Early online date28 Sept 2023
Publication statusPublished - Jan 2024

Bibliographical note

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© 2023 The Authors. Histopathology published by John Wiley & Sons Ltd.


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