Neurologische presentatie van het non-Hodgkin-lymfoom: Een diagnostisch probleem

Translated title of the contribution: Neurological presentation of non-Hodgkin lymphoma: A diagnostic problem

M. J.b. Taphoorn, J. E.C. Bromberg, A. W. Dekker

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)


In two patients, men aged 69 and 38 years, neurological signs were the first presenting symptoms of systemic non-Hodgkin's lymphoma (NHL). This presentation is uncommon. The patients had focal neurological deficit and elevated serum lactate dehydrogenase (LDH) activity. Neurological manifestations of NHL may be caused by extradural lymphoma or by diffuse leptomeningeal metastasis (meningitis lymphomatosa). A third patient, a woman of 48, had a third form of nervous system involvement, primary cerebral NHL, which is not a metastatic sequel to systemic NHL. Primary neurological presentation of NHL may be difficult to diagnose, particularly in case of prior treatment with corticosteroids.

Translated title of the contributionNeurological presentation of non-Hodgkin lymphoma: A diagnostic problem
Original languageDutch
Pages (from-to)1593-1597
Number of pages5
JournalNederlands Tijdschrift voor Geneeskunde
Issue number33
Publication statusPublished - 1997
Externally publishedYes


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