Abstract
The SUPPORT trial evaluated the effect of adding the angiotensin-receptor blocker olmesartan to a combination of angiotensin-converting-enzyme inhibitors and beta-blockers in hypertensive patients with chronic stable heart failure. Unfortunately, this triple renin-angiotensin-aldosterone system blockade was associated with worsening of renal function and increases in cardiac events and mortality.
Original language | Undefined/Unknown |
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Pages (from-to) | 260-261 |
Number of pages | 2 |
Journal | Nature Reviews Nephrology |
Volume | 11 |
Issue number | 5 |
DOIs | |
Publication status | Published - 2015 |