Nomenclature of monocytes and dendritic cells in blood

L Ziegler-Heitbrock; P Ancuta; S Crowe; M Dalod; V Grau; DN Hart; Pieter Leenen; YJ Liu; G MacPherson; GJ Randolph; J Scherberich; J Schmitz; K Shortman; S Sozzani; H Strobl; M Zembala; JM Austyn; MB Lutz

doi:10.1182/blood-2010-02-258558

Nomenclature of monocytes and dendritic cells in blood

L Ziegler-Heitbrock, P Ancuta, S Crowe, M Dalod, V Grau, DN Hart, Pieter Leenen, YJ Liu, G MacPherson, GJ Randolph, J Scherberich, J Schmitz, K Shortman, S Sozzani, H Strobl, M Zembala, JM Austyn, MB Lutz

Immunology

Research output: Contribution to journal › Article › Academic › peer-review

1699 Citations (Scopus)

Abstract

Monocytes and cells of the dendritic cell lineage circulate in blood and eventually migrate into tissue where they further mature and serve various functions, most notably in immune defense. Over recent years these cells have been characterized in detail with the use of cell surface markers and flow cytometry, and subpopulations have been described. The present document proposes a nomenclature for these cells and defines 3 types of monocytes (classical, intermediate, and nonclassical monocytes) and 3 types of dendritic cells (plasmacytoid and 2 types of myeloid dendritic cells) in human and in mouse blood. This classification has been approved by the Nomenclature Committee of the International Union of Immunological Societies, and we are convinced that it will facilitate communication among experts and in the wider scientific community. (Blood.2010;116(16):e74-e80)

Original language	Undefined/Unknown
Pages (from-to)	E74-E80
Journal	Blood
Volume	116
Issue number	16
DOIs	https://doi.org/10.1182/blood-2010-02-258558
Publication status	Published - 2010

Access to Document

10.1182/blood-2010-02-258558

http://hdl.handle.net/1765/27401

Cite this

Ziegler-Heitbrock, L., Ancuta, P., Crowe, S., Dalod, M., Grau, V., Hart, DN., Leenen, P., Liu, YJ., MacPherson, G., Randolph, GJ., Scherberich, J., Schmitz, J., Shortman, K., Sozzani, S., Strobl, H., Zembala, M., Austyn, JM., & Lutz, MB. (2010). Nomenclature of monocytes and dendritic cells in blood. Blood, 116(16), E74-E80. https://doi.org/10.1182/blood-2010-02-258558

@article{a183e4a02e524bcba167861975479b95,

title = "Nomenclature of monocytes and dendritic cells in blood",

abstract = "Monocytes and cells of the dendritic cell lineage circulate in blood and eventually migrate into tissue where they further mature and serve various functions, most notably in immune defense. Over recent years these cells have been characterized in detail with the use of cell surface markers and flow cytometry, and subpopulations have been described. The present document proposes a nomenclature for these cells and defines 3 types of monocytes (classical, intermediate, and nonclassical monocytes) and 3 types of dendritic cells (plasmacytoid and 2 types of myeloid dendritic cells) in human and in mouse blood. This classification has been approved by the Nomenclature Committee of the International Union of Immunological Societies, and we are convinced that it will facilitate communication among experts and in the wider scientific community. (Blood.2010;116(16):e74-e80)",

author = "L Ziegler-Heitbrock and P Ancuta and S Crowe and M Dalod and V Grau and DN Hart and Pieter Leenen and YJ Liu and G MacPherson and GJ Randolph and J Scherberich and J Schmitz and K Shortman and S Sozzani and H Strobl and M Zembala and JM Austyn and MB Lutz",

year = "2010",

doi = "10.1182/blood-2010-02-258558",

language = "Undefined/Unknown",

volume = "116",

pages = "E74--E80",

journal = "Blood",

issn = "0006-4971",

publisher = "American Society of Hematology",

number = "16",

}

TY - JOUR

T1 - Nomenclature of monocytes and dendritic cells in blood

AU - Ziegler-Heitbrock, L

AU - Ancuta, P

AU - Crowe, S

AU - Dalod, M

AU - Grau, V

AU - Hart, DN

AU - Leenen, Pieter

AU - Liu, YJ

AU - MacPherson, G

AU - Randolph, GJ

AU - Scherberich, J

AU - Schmitz, J

AU - Shortman, K

AU - Sozzani, S

AU - Strobl, H

AU - Zembala, M

AU - Austyn, JM

AU - Lutz, MB

PY - 2010

Y1 - 2010

N2 - Monocytes and cells of the dendritic cell lineage circulate in blood and eventually migrate into tissue where they further mature and serve various functions, most notably in immune defense. Over recent years these cells have been characterized in detail with the use of cell surface markers and flow cytometry, and subpopulations have been described. The present document proposes a nomenclature for these cells and defines 3 types of monocytes (classical, intermediate, and nonclassical monocytes) and 3 types of dendritic cells (plasmacytoid and 2 types of myeloid dendritic cells) in human and in mouse blood. This classification has been approved by the Nomenclature Committee of the International Union of Immunological Societies, and we are convinced that it will facilitate communication among experts and in the wider scientific community. (Blood.2010;116(16):e74-e80)

AB - Monocytes and cells of the dendritic cell lineage circulate in blood and eventually migrate into tissue where they further mature and serve various functions, most notably in immune defense. Over recent years these cells have been characterized in detail with the use of cell surface markers and flow cytometry, and subpopulations have been described. The present document proposes a nomenclature for these cells and defines 3 types of monocytes (classical, intermediate, and nonclassical monocytes) and 3 types of dendritic cells (plasmacytoid and 2 types of myeloid dendritic cells) in human and in mouse blood. This classification has been approved by the Nomenclature Committee of the International Union of Immunological Societies, and we are convinced that it will facilitate communication among experts and in the wider scientific community. (Blood.2010;116(16):e74-e80)

U2 - 10.1182/blood-2010-02-258558

DO - 10.1182/blood-2010-02-258558

M3 - Article

SN - 0006-4971

VL - 116

SP - E74-E80

JO - Blood

JF - Blood

IS - 16

ER -