Nonresponder Patients with Hepatitis C Virus Genotype 2/3 Infection: A Question of Low Systemic Interferon Concentrations?

A Alsio, PB Christensen, M Farkkila, N Langeland, MR Buhl, C Pedersen, K Morch, Bart Haagmans, J Westin, K Hellstrand, G Norkrans, M Lagging

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)


Twelve of 303 per-protocol patients were nonresponders in a 12-week versus 24-week treatment study of hepatitis C virus (HCV) genotype 2/3 infection. The nonresponders had significantly lower interferon concentrations, as well as significantly greater mean age, body mass index, and viral load. Suboptimal drug concentrations may thus contribute to lack of response to therapy in patients with infection due to HCV genotype 2/3.
Original languageUndefined/Unknown
Pages (from-to)E22-E25
JournalClinical Infectious Diseases
Issue number4
Publication statusPublished - 2010

Research programs

  • EMC MM-04-27-01

Cite this