TY - JOUR
T1 - Nutritional Management of the Critically Ill Neonate
T2 - A Position Paper of the ESPGHAN Committee on Nutrition
AU - ESPGHAN Committee on Nutrition
AU - Moltu, Sissel Jennifer
AU - Bronsky, Jiri
AU - Embleton, Nicholas
AU - Gerasimidis, Konstantinos
AU - Indrio, Flavia
AU - Köglmeier, Jutta
AU - de Koning, Barbara
AU - Lapillonne, Alexandre
AU - Norsa, Lorenzo
AU - Verduci, Elvira
AU - Domellöf, Magnus
N1 - Publisher Copyright:
Copyright © 2021 by European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition.
PY - 2021/8/1
Y1 - 2021/8/1
N2 - OBJECTIVES: The nutritional management of critically ill term neonates and preterm infants varies widely, and controversies exist in regard to when to initiate nutrition, mode of feeding, energy requirements, and composition of enteral and parenteral feeds. Recommendations for nutritional support in critical illness are needed. METHODS: The ESPGHAN Committee on Nutrition (ESPGHAN-CoN) conducted a systematic literature search on nutritional support in critically ill neonates, including studies on basic metabolism. The Medline database and the Cochrane Library were used in the search for relevant publications. The quality of evidence was reviewed and discussed before voting on recommendations, and a consensus of 90% or more was required for the final approval. Important research gaps were also identified. RESULTS: This position paper provides clinical recommendations on nutritional support during different phases of critical illness in preterm and term neonates based on available literature and expert opinion. CONCLUSION: Basic research along with adequately powered trials are urgently needed to resolve key uncertainties on metabolism and nutrient requirements in this heterogeneous patient population.
AB - OBJECTIVES: The nutritional management of critically ill term neonates and preterm infants varies widely, and controversies exist in regard to when to initiate nutrition, mode of feeding, energy requirements, and composition of enteral and parenteral feeds. Recommendations for nutritional support in critical illness are needed. METHODS: The ESPGHAN Committee on Nutrition (ESPGHAN-CoN) conducted a systematic literature search on nutritional support in critically ill neonates, including studies on basic metabolism. The Medline database and the Cochrane Library were used in the search for relevant publications. The quality of evidence was reviewed and discussed before voting on recommendations, and a consensus of 90% or more was required for the final approval. Important research gaps were also identified. RESULTS: This position paper provides clinical recommendations on nutritional support during different phases of critical illness in preterm and term neonates based on available literature and expert opinion. CONCLUSION: Basic research along with adequately powered trials are urgently needed to resolve key uncertainties on metabolism and nutrient requirements in this heterogeneous patient population.
UR - http://www.scopus.com/inward/record.url?scp=85107201485&partnerID=8YFLogxK
U2 - 10.1097/MPG.0000000000003076
DO - 10.1097/MPG.0000000000003076
M3 - Article
C2 - 33605663
AN - SCOPUS:85107201485
SN - 0277-2116
VL - 73
SP - 274
EP - 289
JO - Journal of Pediatric Gastroenterology and Nutrition
JF - Journal of Pediatric Gastroenterology and Nutrition
IS - 2
ER -