Ongoing mpox outbreak in Kamituga, South Kivu province, associated with monkeypox virus of a novel Clade I sub-lineage, Democratic Republic of the Congo, 2024

Leandre Murhula Masirika*, Jean Claude Udahemuka, Leonard Schuele, Pacifique Ndishimye, Saria Otani, Justin Bengehya Mbiribindi, Jean M. Marekani, Leandre Mutimbwa Mambo, Nadine Malyamungu Bubala, Marjan Boter, David F. Nieuwenhuijse, Trudie Lang, Ernest Balyahamwabo Kalalizi, Jean Pierre Musabyimana, Frank M. Aarestrup, Marion Koopmans, Bas B.Oude Munnink, Freddy Belesi Siangoli

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Abstract

Since the beginning of 2023, the number of people with suspected monkeypox virus (MPXV) infection have sharply increased in the Democratic Republic of the Congo (DRC). We report near-to-complete MPXV genome sequences derived from six cases from the South Kivu province. Phylogenetic analyses reveal that the MPXV affecting the cases belongs to a novel Clade I sub-lineage. The outbreak strain genome lacks the target sequence of the probe and primers of a commonly used Clade I-specific real-time PCR.

Original languageEnglish
JournalEurosurveillance
Volume29
Issue number11
DOIs
Publication statusPublished - 14 Mar 2024

Bibliographical note

Publisher Copyright:
© 2024 European Centre for Disease Prevention and Control (ECDC). All rights reserved.

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