Outcome of Pregnancy in Women With Congenital Heart Disease.: A Literature Review

Willem Drenthen; Petronella G. Pieper; Jolien W. Roos-Hesselink; Willem A. van Lottum; Adriaan A. Voors; Barbara J.M. Mulder; Arie P.J. van Dijk; Hubert W. Vliegen; Sing C. Yap; Philip Moons; Tjark Ebels; Dirk J. van Veldhuisen

doi:10.1016/j.jacc.2007.03.027

Outcome of Pregnancy in Women With Congenital Heart Disease. A Literature Review

Willem Drenthen^*
, Petronella G. Pieper
, Jolien W. Roos-Hesselink
, Willem A. van Lottum
, Adriaan A. Voors
, Barbara J.M. Mulder
, Arie P.J. van Dijk
, Hubert W. Vliegen
, Sing C. Yap
, Philip Moons
, Tjark Ebels
, Dirk J. van Veldhuisen

^*Corresponding author for this work

Cardiology

University Medical Centre Groningen
Amsterdam UMC
Radboud University Medical Center
Leiden University Medical Centre
University Hospitals Leuven

Research output: Contribution to journal › Article › Academic › peer-review

559 Citations (Scopus)

Abstract

A search of peer-reviewed literature was conducted to identify reports that provide data on complications associated with pregnancy in women with structural congenital heart disease (CHD). This review describes the outcome of 2,491 pregnancies, including 377 miscarriages (15%) and 114 elective abortions (5%). Important cardiac complications were seen in 11% of the pregnancies. Obstetric complications do not appear to be more prevalent. In complex CHD, premature delivery rates are high, and more children are small for gestational age. The offspring mortality was high throughout the spectrum and was related to the relatively high rate of premature delivery and recurrence of CHD.

Original language	English
Pages (from-to)	2303-2311
Number of pages	9
Journal	Journal of the American College of Cardiology
Volume	49
Issue number	24
DOIs	https://doi.org/10.1016/j.jacc.2007.03.027
Publication status	Published - 19 Jun 2007

Bibliographical note

Funding Information:
Supported by Netherlands Heart Foundation Grant 2002 B125 to Dr. Pieper and by the Interuniversity Cardiology Institute, the Netherlands (ICIN).

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10.1016/j.jacc.2007.03.027

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Drenthen, W., Pieper, P. G., Roos-Hesselink, J. W., van Lottum, W. A., Voors, A. A., Mulder, B. J. M., van Dijk, A. P. J., Vliegen, H. W., Yap, S. C., Moons, P., Ebels, T., & van Veldhuisen, D. J. (2007). Outcome of Pregnancy in Women With Congenital Heart Disease. A Literature Review. Journal of the American College of Cardiology, 49(24), 2303-2311. https://doi.org/10.1016/j.jacc.2007.03.027

@article{f16b6b1260934b449f70a0d115d3eb09,

title = "Outcome of Pregnancy in Women With Congenital Heart Disease.: A Literature Review",

abstract = "A search of peer-reviewed literature was conducted to identify reports that provide data on complications associated with pregnancy in women with structural congenital heart disease (CHD). This review describes the outcome of 2,491 pregnancies, including 377 miscarriages (15\%) and 114 elective abortions (5\%). Important cardiac complications were seen in 11\% of the pregnancies. Obstetric complications do not appear to be more prevalent. In complex CHD, premature delivery rates are high, and more children are small for gestational age. The offspring mortality was high throughout the spectrum and was related to the relatively high rate of premature delivery and recurrence of CHD.",

author = "Willem Drenthen and Pieper, \{Petronella G.\} and Roos-Hesselink, \{Jolien W.\} and \{van Lottum\}, \{Willem A.\} and Voors, \{Adriaan A.\} and Mulder, \{Barbara J.M.\} and \{van Dijk\}, \{Arie P.J.\} and Vliegen, \{Hubert W.\} and Yap, \{Sing C.\} and Philip Moons and Tjark Ebels and \{van Veldhuisen\}, \{Dirk J.\}",

note = "Funding Information: Supported by Netherlands Heart Foundation Grant 2002 B125 to Dr. Pieper and by the Interuniversity Cardiology Institute, the Netherlands (ICIN). ",

year = "2007",

month = jun,

day = "19",

doi = "10.1016/j.jacc.2007.03.027",

language = "English",

volume = "49",

pages = "2303--2311",

journal = "Journal of the American College of Cardiology",

issn = "0735-1097",

publisher = "Elsevier Inc.",

number = "24",

}

Drenthen, W, Pieper, PG, Roos-Hesselink, JW, van Lottum, WA, Voors, AA, Mulder, BJM, van Dijk, APJ, Vliegen, HW, Yap, SC, Moons, P, Ebels, T & van Veldhuisen, DJ 2007, 'Outcome of Pregnancy in Women With Congenital Heart Disease. A Literature Review', Journal of the American College of Cardiology, vol. 49, no. 24, pp. 2303-2311. https://doi.org/10.1016/j.jacc.2007.03.027

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T1 - Outcome of Pregnancy in Women With Congenital Heart Disease.

T2 - A Literature Review

AU - Drenthen, Willem

AU - Pieper, Petronella G.

AU - Roos-Hesselink, Jolien W.

AU - van Lottum, Willem A.

AU - Voors, Adriaan A.

AU - Mulder, Barbara J.M.

AU - van Dijk, Arie P.J.

AU - Vliegen, Hubert W.

AU - Yap, Sing C.

AU - Moons, Philip

AU - Ebels, Tjark

AU - van Veldhuisen, Dirk J.

N1 - Funding Information: Supported by Netherlands Heart Foundation Grant 2002 B125 to Dr. Pieper and by the Interuniversity Cardiology Institute, the Netherlands (ICIN).

PY - 2007/6/19

Y1 - 2007/6/19

N2 - A search of peer-reviewed literature was conducted to identify reports that provide data on complications associated with pregnancy in women with structural congenital heart disease (CHD). This review describes the outcome of 2,491 pregnancies, including 377 miscarriages (15%) and 114 elective abortions (5%). Important cardiac complications were seen in 11% of the pregnancies. Obstetric complications do not appear to be more prevalent. In complex CHD, premature delivery rates are high, and more children are small for gestational age. The offspring mortality was high throughout the spectrum and was related to the relatively high rate of premature delivery and recurrence of CHD.

AB - A search of peer-reviewed literature was conducted to identify reports that provide data on complications associated with pregnancy in women with structural congenital heart disease (CHD). This review describes the outcome of 2,491 pregnancies, including 377 miscarriages (15%) and 114 elective abortions (5%). Important cardiac complications were seen in 11% of the pregnancies. Obstetric complications do not appear to be more prevalent. In complex CHD, premature delivery rates are high, and more children are small for gestational age. The offspring mortality was high throughout the spectrum and was related to the relatively high rate of premature delivery and recurrence of CHD.

UR - https://www.scopus.com/pages/publications/34249998093

U2 - 10.1016/j.jacc.2007.03.027

DO - 10.1016/j.jacc.2007.03.027

M3 - Article

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AN - SCOPUS:34249998093

SN - 0735-1097

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EP - 2311

JO - Journal of the American College of Cardiology

JF - Journal of the American College of Cardiology

IS - 24

ER -

Outcome of Pregnancy in Women With Congenital Heart Disease. A Literature Review

Abstract

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