Parallel genome analysis by two-dimensional DNA typing.

E. Mullaart*, G. J. de Vos, G. J. te Meerman, A. G. Uitterlinden, J. Vijg

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

19 Citations (Scopus)


By two-dimensional (2-D) DNA typing a restriction enzyme digest of genomic DNA can be resolved on the basis of both size and base-pair sequence and subsequently analysed by repeat probe hybridization to reveal sequence variants at multiple genomic sites in parallel. The system has been partly automated and allows for large-scale comparative analysis of complex genomes in a cost-effective manner.

Original languageEnglish
Pages (from-to)469-471
Number of pages3
Issue number6445
Publication statusPublished - 30 Sept 1993
Externally publishedYes


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