Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation

AB Brinkman; S Nik-Zainal; F Simmer; Francisco Rodriguez Gonzalez; Marcel Smid; LB Alexandrov; A Butler; S Martink; H Davies; D Glodzik; X Q Zou; M Ramakrishna; J Staaf; M Ringrier; Anieta Sieuwerts; A Ferrari; S Morganella; T Fleischer; V Kristensen; M Gut; MJ van de Vijver; AL Borresen-Dale; AL Richardson; G Thomas; I G Gut; John Martens; John Foekens; MR Stratton; HG Stunnenberg

doi:10.1038/s41467-019-09828-0

Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation

AB Brinkman, S Nik-Zainal, F Simmer, Francisco Rodriguez Gonzalez, Marcel Smid, LB Alexandrov, A Butler, S Martink, H Davies, D Glodzik, X Q Zou, M Ramakrishna, J Staaf, M Ringrier, Anieta Sieuwerts, A Ferrari, S Morganella, T Fleischer, V Kristensen, M GutMJ van de Vijver, AL Borresen-Dale, AL Richardson, G Thomas, I G Gut, John Martens, John Foekens, MR Stratton, HG Stunnenberg

Medical Oncology

Research output: Contribution to journal › Article › Academic › peer-review

39 Citations (Scopus)

25 Downloads (Pure)

Original language	Undefined/Unknown
Article number	1749
Journal	Nature Communications
Volume	10
DOIs	https://doi.org/10.1038/s41467-019-09828-0
Publication status	Published - 2019

Research programs

EMC MM-03-86-01

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1038/s41467-019-09828-0

Repub_116251_O-A.pdfFinal published version, 1.54 MB

http://hdl.handle.net/1765/116251

Cite this

Brinkman, AB., Nik-Zainal, S., Simmer, F., Rodriguez Gonzalez, F., Smid, M., Alexandrov, LB., Butler, A., Martink, S., Davies, H., Glodzik, D., Zou, X. Q., Ramakrishna, M., Staaf, J., Ringrier, M., Sieuwerts, A., Ferrari, A., Morganella, S., Fleischer, T., Kristensen, V., ... Stunnenberg, HG. (2019). Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation. Nature Communications, 10, Article 1749. https://doi.org/10.1038/s41467-019-09828-0

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doi = "10.1038/s41467-019-09828-0",

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journal = "Nature Communications",

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Brinkman, AB, Nik-Zainal, S, Simmer, F, Rodriguez Gonzalez, F, Smid, M, Alexandrov, LB, Butler, A, Martink, S, Davies, H, Glodzik, D, Zou, XQ, Ramakrishna, M, Staaf, J, Ringrier, M, Sieuwerts, A, Ferrari, A, Morganella, S, Fleischer, T, Kristensen, V, Gut, M, van de Vijver, MJ, Borresen-Dale, AL, Richardson, AL, Thomas, G, Gut, IG, Martens, J, Foekens, J, Stratton, MR & Stunnenberg, HG 2019, 'Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation', Nature Communications, vol. 10, 1749. https://doi.org/10.1038/s41467-019-09828-0

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T1 - Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation

AU - Brinkman, AB

AU - Nik-Zainal, S

AU - Simmer, F

AU - Rodriguez Gonzalez, Francisco

AU - Smid, Marcel

AU - Alexandrov, LB

AU - Butler, A

AU - Martink, S

AU - Davies, H

AU - Glodzik, D

AU - Zou, X Q

AU - Ramakrishna, M

AU - Staaf, J

AU - Ringrier, M

AU - Sieuwerts, Anieta

AU - Ferrari, A

AU - Morganella, S

AU - Fleischer, T

AU - Kristensen, V

AU - Gut, M

AU - van de Vijver, MJ

AU - Borresen-Dale, AL

AU - Richardson, AL

AU - Thomas, G

AU - Gut, I G

AU - Martens, John

AU - Foekens, John

AU - Stratton, MR

AU - Stunnenberg, HG

PY - 2019

Y1 - 2019

U2 - 10.1038/s41467-019-09828-0

DO - 10.1038/s41467-019-09828-0

M3 - Article

C2 - 30988298

SN - 2041-1723

VL - 10

JO - Nature Communications

JF - Nature Communications

M1 - 1749

ER -