Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation

AB Brinkman; S Nik-Zainal; F Simmer; Francisco Rodriguez Gonzalez; Marcel Smid; LB Alexandrov; A Butler; S Martink; H Davies; D Glodzik; X Q Zou; M Ramakrishna; J Staaf; M Ringrier; Anieta Sieuwerts; A Ferrari; S Morganella; T Fleischer; V Kristensen; M Gut; MJ van de Vijver; AL Borresen-Dale; AL Richardson; G Thomas; I G Gut; John Martens; John Foekens; MR Stratton; HG Stunnenberg

doi:10.1038/s41467-019-09828-0

Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation

AB Brinkman
, S Nik-Zainal
, F Simmer
, Francisco Rodriguez Gonzalez
, Marcel Smid
, LB Alexandrov
, A Butler
, S Martink
, H Davies
, D Glodzik
, X Q Zou
, M Ramakrishna
, J Staaf
, M Ringrier
, Anieta Sieuwerts
, A Ferrari
, S Morganella
, T Fleischer
, V Kristensen
, M Gut

MJ van de Vijver, AL Borresen-Dale, AL Richardson, G Thomas, I G Gut, John Martens, John Foekens, MR Stratton, HG Stunnenberg

Medical Oncology

Research output: Contribution to journal › Article › Academic › peer-review

51 Citations (Scopus)

71 Downloads (Pure)

Original language	Undefined/Unknown
Article number	1749
Journal	Nature Communications
Volume	10
DOIs	https://doi.org/10.1038/s41467-019-09828-0
Publication status	Published - 2019

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Research programs

EMC MM-03-86-01

Access to Document

10.1038/s41467-019-09828-0

Repub_116251_O-A.pdfFinal published version, 1.54 MB

http://hdl.handle.net/1765/116251

Cite this

Brinkman, AB., Nik-Zainal, S., Simmer, F., Rodriguez Gonzalez, F., Smid, M., Alexandrov, LB., Butler, A., Martink, S., Davies, H., Glodzik, D., Zou, X. Q., Ramakrishna, M., Staaf, J., Ringrier, M., Sieuwerts, A., Ferrari, A., Morganella, S., Fleischer, T., Kristensen, V., ... Stunnenberg, HG. (2019). Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation. Nature Communications, 10, Article 1749. https://doi.org/10.1038/s41467-019-09828-0

@article{f5331f98e58544768663ba580c46d126,

title = "Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation",

author = "AB Brinkman and S Nik-Zainal and F Simmer and \{Rodriguez Gonzalez\}, Francisco and Marcel Smid and LB Alexandrov and A Butler and S Martink and H Davies and D Glodzik and Zou, \{X Q\} and M Ramakrishna and J Staaf and M Ringrier and Anieta Sieuwerts and A Ferrari and S Morganella and T Fleischer and V Kristensen and M Gut and \{van de Vijver\}, MJ and AL Borresen-Dale and AL Richardson and G Thomas and Gut, \{I G\} and John Martens and John Foekens and MR Stratton and HG Stunnenberg",

year = "2019",

doi = "10.1038/s41467-019-09828-0",

language = "Undefined/Unknown",

volume = "10",

journal = "Nature Communications",

issn = "2041-1723",

publisher = "Nature Research",

}

Brinkman, AB, Nik-Zainal, S, Simmer, F, Rodriguez Gonzalez, F, Smid, M, Alexandrov, LB, Butler, A, Martink, S, Davies, H, Glodzik, D, Zou, XQ, Ramakrishna, M, Staaf, J, Ringrier, M, Sieuwerts, A, Ferrari, A, Morganella, S, Fleischer, T, Kristensen, V, Gut, M, van de Vijver, MJ, Borresen-Dale, AL, Richardson, AL, Thomas, G, Gut, IG, Martens, J, Foekens, J, Stratton, MR & Stunnenberg, HG 2019, 'Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation', Nature Communications, vol. 10, 1749. https://doi.org/10.1038/s41467-019-09828-0

TY - JOUR

T1 - Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation

AU - Brinkman, AB

AU - Nik-Zainal, S

AU - Simmer, F

AU - Rodriguez Gonzalez, Francisco

AU - Smid, Marcel

AU - Alexandrov, LB

AU - Butler, A

AU - Martink, S

AU - Davies, H

AU - Glodzik, D

AU - Zou, X Q

AU - Ramakrishna, M

AU - Staaf, J

AU - Ringrier, M

AU - Sieuwerts, Anieta

AU - Ferrari, A

AU - Morganella, S

AU - Fleischer, T

AU - Kristensen, V

AU - Gut, M

AU - van de Vijver, MJ

AU - Borresen-Dale, AL

AU - Richardson, AL

AU - Thomas, G

AU - Gut, I G

AU - Martens, John

AU - Foekens, John

AU - Stratton, MR

AU - Stunnenberg, HG

PY - 2019

Y1 - 2019

U2 - 10.1038/s41467-019-09828-0

DO - 10.1038/s41467-019-09828-0

M3 - Article

C2 - 30988298

SN - 2041-1723

VL - 10

JO - Nature Communications

JF - Nature Communications

M1 - 1749

ER -