Pathophysiology of nerve regeneration and nerve reconstruction in burned patients

JH Coert

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)


In extensive burns peripheral nerves can be involved. The injury to the nerve can be direct by thermal or electrical burns, but nerves can also be indirectly affected by the systemic reaction that follows the burn. Mediators will be released causing a neuropathy to nerves remote from the involved area. Involved mediators and possible therapeutic options will be discussed. In burned patients nerves can be reconstructed using autologous nerve grafts or nerve conduits. A key factor is an adequate wound debridement and a well-vascularized bed to optimize the outgrowth of the axons. Early free tissue transfers have shown promising results. (C) 2009 Elsevier Ltd and ISBI. All rights reserved.
Original languageUndefined/Unknown
Pages (from-to)593-598
Number of pages6
Issue number5
Publication statusPublished - 2010

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