Patient-derived oral mucosa organoids as an in vitro model for methotrexate induced toxicity in pediatric acute lymphoblastic leukemia

E Driehuis; N Oosterom; Sandra Heil; IB Muller; M Lin; S Kolders; G Jansen; R de Jonge; Rob Pieters; H Clevers; Marry Van den Heuvel - Eibrink

doi:10.1371/journal.pone.0231588

Patient-derived oral mucosa organoids as an in vitro model for methotrexate induced toxicity in pediatric acute lymphoblastic leukemia

E Driehuis
, N Oosterom
, Sandra Heil
, IB Muller
, M Lin
, S Kolders
, G Jansen
, R de Jonge
, Rob Pieters
, H Clevers
, Marry Van den Heuvel - Eibrink

Clinical Chemistry

External organisation

Research output: Contribution to journal › Article › Academic › peer-review

32 Citations (Scopus)

37 Downloads (Pure)

Original language	English
Article number	e0231588
Journal	PLoS One (print)
Volume	15
Issue number	5
DOIs	https://doi.org/10.1371/journal.pone.0231588
Publication status	Published - 2020

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Driehuis, E., Oosterom, N., Heil, S., Muller, IB., Lin, M., Kolders, S., Jansen, G., de Jonge, R., Pieters, R., Clevers, H., & Van den Heuvel - Eibrink, M. (2020). Patient-derived oral mucosa organoids as an in vitro model for methotrexate induced toxicity in pediatric acute lymphoblastic leukemia. PLoS One (print), 15(5), Article e0231588. https://doi.org/10.1371/journal.pone.0231588

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Driehuis, E, Oosterom, N, Heil, S, Muller, IB, Lin, M, Kolders, S, Jansen, G, de Jonge, R, Pieters, R, Clevers, H & Van den Heuvel - Eibrink, M 2020, 'Patient-derived oral mucosa organoids as an in vitro model for methotrexate induced toxicity in pediatric acute lymphoblastic leukemia', PLoS One (print), vol. 15, no. 5, e0231588. https://doi.org/10.1371/journal.pone.0231588

TY - JOUR

T1 - Patient-derived oral mucosa organoids as an in vitro model for methotrexate induced toxicity in pediatric acute lymphoblastic leukemia

AU - Driehuis, E

AU - Oosterom, N

AU - Heil, Sandra

AU - Muller, IB

AU - Lin, M

AU - Kolders, S

AU - Jansen, G

AU - de Jonge, R

AU - Pieters, Rob

AU - Clevers, H

AU - Van den Heuvel - Eibrink, Marry

PY - 2020

Y1 - 2020

U2 - 10.1371/journal.pone.0231588

DO - 10.1371/journal.pone.0231588

M3 - Article

C2 - 32421698

SN - 1932-6203

VL - 15

JO - PLoS One (print)

JF - PLoS One (print)

IS - 5

M1 - e0231588

ER -