Patients with cystic fibrosis have a high carriage rate of non-toxigenic Clostridium difficile

MP Bauer, A Farid, Marleen Bakker, R.A.S. Hoek, EJ Kuijper, JT van Dissel

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Thirty-year-old observations report frequent asymptomatic Clostridium difficile carriage among cystic fibrosis (CF) patients. In this case-control study, we found more carriers among CF patients than controls (47% versus 11%), but most strains carried by CF patients were non-toxigenic (77% versus 17%). Among CF patients, carriers were younger, with more severe pulmonary disease than non-carriers. Strains belonged to multiple PCR-ribotypes, suggesting that these CF patients did not acquire strains from each other.
Original languageUndefined/Unknown
Pages (from-to)O446-O449
JournalClinical Microbiology and Infection
Issue number7
Publication statusPublished - 2014

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