Perinatal Infections With Ureaplasma

Kim Stol*, Jop Jans, Lisa Ott de Bruin, Wendy Unger, Annemarie van Rossum

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

8 Citations (Scopus)
74 Downloads (Pure)


Ureaplasma species are increasingly recognized as relevant pathogens in prenatal, perinatal and postnatal morbidity. They are commonly found as commensals on the mucous membranes of the lower urogenital tract of pregnant women, but when ascending, they can cause bacterial vaginosis, chorioamnionitis, premature birth and postnatal morbidities such as bronchopulmonary dysplasia, and early-onset neonatal sepsis and meningitis. The detection of Ureaplasma species is challenging and is not covered by routine diagnostics, and current empiric antibiotic treatment in neonates suspected of infection is not directed against Ureaplasma species. The aim of this review is to discuss the pathophysiology of Ureaplasma infections, the clinical consequences and the current difficulties in diagnosis and treatment by providing an overview of the current literature.

Original languageEnglish
Pages (from-to)S26-S30
JournalThe Pediatric infectious disease journal
Issue number5S
Publication statusPublished - May 2021

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Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.


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