TY - JOUR
T1 - Persistent Annual Permanent Pacemaker Implantation Rate After Surgical Aortic Valve Replacement in Patients With Severe Aortic Stenosis
AU - Mieghem, Nicolas
AU - Head, Stuart
AU - Jong, Wesley
AU - Domburg, Ron
AU - Serruys, PWJC (Patrick)
AU - Jaegere, Peter
AU - Jordaens, Luc
AU - Takkenberg, Hanneke
AU - Bogers, Ad
AU - Kappetein, Arie-Pieter
PY - 2012
Y1 - 2012
N2 - Background. Degenerative aortic valve stenosis (AS) is associated with conduction abnormalities. Pacemaker implantation is encountered after surgical aortic valve replacement (SAVR). Not much is known about the pacemaker implantation rate during midterm follow-up after SAVR. Our objectives were to determine the incidence of permanent pacemaker implantation (PPI) in the midterm after SAVR in a tertiary care facility. Methods. We reviewed procedural data of 734 consecutive patients (56% men; mean age, 68.9 +/- 9.5 years) with degenerative severe AS who underwent SAVR between January 1, 2003, and December 31, 2008. Perioperative electrocardiograms were assessed for occurrence of conduction abnormalities, and we sought to determine the incidence and indication for PPI with a median follow-up of 3.76 years (interquartile range, 2.44 to 5.59 years). Univariate and multivariate logistic regression models were appl Results. Isolated SAVR was performed in 56%, SAVR with coronary artery bypass grafting in 35%, and SAVR with any other valve therapy in 5.8%. Complete bundle branch block (BBB) was present in 7% and first-degree atrioventricular block in 11%. New BBBs were detected in 63 patients (8.6%). Fifteen patients (2.0%) required a PPI within 30 days after SAVR, and 28 (4.0%) underwent PPI more than 30 days after SAVR. The linearized rate of PPI after SAVR was 1.01% +/- 0.37% per patient-year. Patients wi Conclusions. Patients with severe AS who underwent SAVR have a persistent 1% annual risk for PPI. Postoperative presence of BBB predicted the need for PPI both within 30 days and after 30 days after SAVR. (Ann Thorac Surg 2012;94:1143-9) (C) 2012 by The Society of Thoracic Surgeons
AB - Background. Degenerative aortic valve stenosis (AS) is associated with conduction abnormalities. Pacemaker implantation is encountered after surgical aortic valve replacement (SAVR). Not much is known about the pacemaker implantation rate during midterm follow-up after SAVR. Our objectives were to determine the incidence of permanent pacemaker implantation (PPI) in the midterm after SAVR in a tertiary care facility. Methods. We reviewed procedural data of 734 consecutive patients (56% men; mean age, 68.9 +/- 9.5 years) with degenerative severe AS who underwent SAVR between January 1, 2003, and December 31, 2008. Perioperative electrocardiograms were assessed for occurrence of conduction abnormalities, and we sought to determine the incidence and indication for PPI with a median follow-up of 3.76 years (interquartile range, 2.44 to 5.59 years). Univariate and multivariate logistic regression models were appl Results. Isolated SAVR was performed in 56%, SAVR with coronary artery bypass grafting in 35%, and SAVR with any other valve therapy in 5.8%. Complete bundle branch block (BBB) was present in 7% and first-degree atrioventricular block in 11%. New BBBs were detected in 63 patients (8.6%). Fifteen patients (2.0%) required a PPI within 30 days after SAVR, and 28 (4.0%) underwent PPI more than 30 days after SAVR. The linearized rate of PPI after SAVR was 1.01% +/- 0.37% per patient-year. Patients wi Conclusions. Patients with severe AS who underwent SAVR have a persistent 1% annual risk for PPI. Postoperative presence of BBB predicted the need for PPI both within 30 days and after 30 days after SAVR. (Ann Thorac Surg 2012;94:1143-9) (C) 2012 by The Society of Thoracic Surgeons
U2 - 10.1016/j.athoracsur.2012.04.038
DO - 10.1016/j.athoracsur.2012.04.038
M3 - Article
SN - 0003-4975
VL - 94
SP - 1143
EP - 1149
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
IS - 4
ER -