Phase I pharmacokinetic, food effect, and pharmacogenetic study of oral irinotecan given as semisolid matrix capsules in patients with solid tumors

O Soepenberg; H Dumez; Jaap Verweij; FA (Floris) de Jong; Maja de Jonge; J Thomas; Ferry Eskens; Ron van Schaik; J Selleslach; J Steeg; P Lefebvre; S Assadourian; GJ Sanderink; A Sparreboom; AT van Oosterom

doi:10.1158/1078-0432.CCR-04-1758

Phase I pharmacokinetic, food effect, and pharmacogenetic study of oral irinotecan given as semisolid matrix capsules in patients with solid tumors

O Soepenberg, H Dumez, Jaap Verweij, FA (Floris) de Jong, Maja de Jonge, J Thomas, Ferry Eskens, Ron van Schaik, J Selleslach, J Steeg, P Lefebvre, S Assadourian, GJ Sanderink, A Sparreboom, AT van Oosterom

External organisation

Research output: Contribution to journal › Article › Academic › peer-review

33 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	1504-1511
Number of pages	8
Journal	Clinical Cancer Research
Volume	11
Issue number	4
DOIs	https://doi.org/10.1158/1078-0432.CCR-04-1758
Publication status	Published - 2005

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EMC MM-03-86-08
EMC OR-01-25-01

Access to Document

10.1158/1078-0432.CCR-04-1758

http://hdl.handle.net/1765/13711

Cite this

Soepenberg, O., Dumez, H., Verweij, J., de Jong, FA., de Jonge, M., Thomas, J., Eskens, F., van Schaik, R., Selleslach, J., Steeg, J., Lefebvre, P., Assadourian, S., Sanderink, GJ., Sparreboom, A., & van Oosterom, AT. (2005). Phase I pharmacokinetic, food effect, and pharmacogenetic study of oral irinotecan given as semisolid matrix capsules in patients with solid tumors. Clinical Cancer Research, 11(4), 1504-1511. https://doi.org/10.1158/1078-0432.CCR-04-1758

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Soepenberg, O, Dumez, H, Verweij, J, de Jong, FA, de Jonge, M, Thomas, J, Eskens, F , van Schaik, R, Selleslach, J, Steeg, J, Lefebvre, P, Assadourian, S, Sanderink, GJ, Sparreboom, A & van Oosterom, AT 2005, 'Phase I pharmacokinetic, food effect, and pharmacogenetic study of oral irinotecan given as semisolid matrix capsules in patients with solid tumors', Clinical Cancer Research, vol. 11, no. 4, pp. 1504-1511. https://doi.org/10.1158/1078-0432.CCR-04-1758

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T1 - Phase I pharmacokinetic, food effect, and pharmacogenetic study of oral irinotecan given as semisolid matrix capsules in patients with solid tumors

AU - Soepenberg, O

AU - Dumez, H

AU - Verweij, Jaap

AU - de Jong, FA (Floris)

AU - de Jonge, Maja

AU - Thomas, J

AU - Eskens, Ferry

AU - van Schaik, Ron

AU - Selleslach, J

AU - Steeg, J

AU - Lefebvre, P

AU - Assadourian, S

AU - Sanderink, GJ

AU - Sparreboom, A

AU - van Oosterom, AT

PY - 2005

Y1 - 2005

U2 - 10.1158/1078-0432.CCR-04-1758

DO - 10.1158/1078-0432.CCR-04-1758

M3 - Article

C2 - 15746053

SN - 1078-0432

VL - 11

SP - 1504

EP - 1511

JO - Clinical Cancer Research

JF - Clinical Cancer Research

IS - 4

ER -