@inproceedings{6117efb2acfe4a6b948997553e736c78,
title = "Photoacoustic imaging of tumor angiogenesis",
abstract = "Photoacoustic imaging is a hybrid imaging modality that is based on the detection of acoustic waves generated by absorption of pulsed light by tissue chromophores such as hemoglobin in blood. Serial photoacoustic imaging has been performed over a 10-day period after subcutaneous inoculation of pancreatic tumor cells in a rat. The images were obtained from ultrasound generated by absorption in hemoglobin of short laser pulses at a wavelength of 1064 nm. The ultrasound signals were measured in reflection mode using a double-ring photoacoustic detector. A correction algorithm has been developed to correct for scanning and movement artifacts during the measurements. Three-dimensional data visualize the development and quantify the extent of individual blood vessels around the growing tumor, blood concentration changes inside the tumor and growth in depth of the neovascularized region.",
author = "Kolkman, {Roy G.M.} and Thumma, {Kiran K.} and {Ten Brinke}, {Gerbert A.} and Siphanto, {Ronald I.} and {Van Neck}, Han and Wiendelt Steenbergen and {Van Leeuwen}, {Ton G.}",
year = "2008",
doi = "10.1117/12.761214",
language = "English",
isbn = "9780819470317",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
booktitle = "Photons Plus Ultrasound",
note = "9th Conference on Photons Plus Ultrasound: Imaging and Sensing 2008 ; Conference date: 20-01-2008 Through 23-01-2008",
}