Polygenic risk scores for melanoma: a stepwise process towards clinical implementation

Marlies Wakkee*

*Corresponding author for this work

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

1 Citation (Scopus)
37 Downloads (Pure)

Abstract

Early detection of melanoma or, even better, preventing mela-noma by educating and stimulating sun-protective behaviour,are still essential steps to reducing its global burden. However,evidence is insufficient to demonstrate the benefit of popula-tion-based screening by total body skin examination.1Poten-tially, focusing the screening on high-risk individuals may becost effective. Clinical implementation of polygenic risk scores(PRSs) is increasingly mentioned to facilitate this identificationof high-risk individuals (i.e. genetic risk stratification). [...]
Original languageEnglish
Pages (from-to)768
Number of pages1
JournalBritish Journal of Dermatology
Volume186
Issue number5
Early online date2 May 2022
DOIs
Publication statusPublished - May 2022

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