Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis

TF Gendron; J Chew; JN Stankowski; LR Hayes; YJ Zhang; M Prudencio; Y Carlomagno; LM Daughrity; K Jansen-West; EA Perkerson; A O'Raw; C Cook; L Pregent; V Belzil; M van Blitterswijk; LJ Tabassian; CW Lee; M Yue; JM Tong; YP Song; M Castanedes-Casey; L Rousseau; V Phillips; DW Dickson; R Rademakers; JD Fryer; BK Rush; O Pedraza; AM Caputo; P Desaro; C Palmucci; A Robertson; MG Heckman; NN Diehl; E Wiggs; M Tierney; L Braun; J Farren; D Lacomis; S Ladha; CN Fournier; LF McCluskey; LB Elman; JB Toledo; JD McBride; C Tiloca; C Morelli; B Poletti; F Solca; A Prelle; J Wuu; J Jockel-Balsarotti; F Rigo; C Ambrose; A Datta; WX Yang; D Raitcheva; G Antognetti; A McCampbell; J.C. van Swieten; BL Miller; AL Boxer; RH Brown; R Bowser; TM Miller; JQ Trojanowski; M Grossman; J D Berry; WT Hu; A Ratti; BJ Traynor; MD Disney; M Benatar; V Silani; JD Glass; MK Floeter; JD Rothstein; KB Boylan; L Petrucelli

doi:10.1126/scitranslmed.aai7866

Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis

TF Gendron, J Chew, JN Stankowski, LR Hayes, YJ Zhang, M Prudencio, Y Carlomagno, LM Daughrity, K Jansen-West, EA Perkerson, A O'Raw, C Cook, L Pregent, V Belzil, M van Blitterswijk, LJ Tabassian, CW Lee, M Yue, JM Tong, YP SongM Castanedes-Casey, L Rousseau, V Phillips, DW Dickson, R Rademakers, JD Fryer, BK Rush, O Pedraza, AM Caputo, P Desaro, C Palmucci, A Robertson, MG Heckman, NN Diehl, E Wiggs, M Tierney, L Braun, J Farren, D Lacomis, S Ladha, CN Fournier, LF McCluskey, LB Elman, JB Toledo, JD McBride, C Tiloca, C Morelli, B Poletti, F Solca, A Prelle, J Wuu, J Jockel-Balsarotti, F Rigo, C Ambrose, A Datta, WX Yang, D Raitcheva, G Antognetti, A McCampbell, J.C. van Swieten, BL Miller, AL Boxer, RH Brown, R Bowser, TM Miller, JQ Trojanowski, M Grossman, J D Berry, WT Hu, A Ratti, BJ Traynor, MD Disney, M Benatar, V Silani, JD Glass, MK Floeter, JD Rothstein, KB Boylan, L Petrucelli

Neurology

Research output: Contribution to journal › Article › Academic › peer-review

169 Citations (Scopus)

Original language	Undefined/Unknown
Article number	eaai7866
Journal	Science Translational Medicine
Volume	9
Issue number	383
DOIs	https://doi.org/10.1126/scitranslmed.aai7866
Publication status	Published - 2017

Research programs

EMC OR-01

Access to Document

10.1126/scitranslmed.aai7866

http://hdl.handle.net/1765/99274

Cite this

Gendron, TF., Chew, J., Stankowski, JN., Hayes, LR., Zhang, YJ., Prudencio, M., Carlomagno, Y., Daughrity, LM., Jansen-West, K., Perkerson, EA., O'Raw, A., Cook, C., Pregent, L., Belzil, V., van Blitterswijk, M., Tabassian, LJ., Lee, CW., Yue, M., Tong, JM., ... Petrucelli, L. (2017). Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis. Science Translational Medicine, 9(383), Article eaai7866. https://doi.org/10.1126/scitranslmed.aai7866

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title = "Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis",

author = "TF Gendron and J Chew and JN Stankowski and LR Hayes and YJ Zhang and M Prudencio and Y Carlomagno and LM Daughrity and K Jansen-West and EA Perkerson and A O'Raw and C Cook and L Pregent and V Belzil and {van Blitterswijk}, M and LJ Tabassian and CW Lee and M Yue and JM Tong and YP Song and M Castanedes-Casey and L Rousseau and V Phillips and DW Dickson and R Rademakers and JD Fryer and BK Rush and O Pedraza and AM Caputo and P Desaro and C Palmucci and A Robertson and MG Heckman and NN Diehl and E Wiggs and M Tierney and L Braun and J Farren and D Lacomis and S Ladha and CN Fournier and LF McCluskey and LB Elman and JB Toledo and JD McBride and C Tiloca and C Morelli and B Poletti and F Solca and A Prelle and J Wuu and J Jockel-Balsarotti and F Rigo and C Ambrose and A Datta and WX Yang and D Raitcheva and G Antognetti and A McCampbell and {van Swieten}, J.C. and BL Miller and AL Boxer and RH Brown and R Bowser and TM Miller and JQ Trojanowski and M Grossman and Berry, {J D} and WT Hu and A Ratti and BJ Traynor and MD Disney and M Benatar and V Silani and JD Glass and MK Floeter and JD Rothstein and KB Boylan and L Petrucelli",

year = "2017",

doi = "10.1126/scitranslmed.aai7866",

language = "Undefined/Unknown",

volume = "9",

journal = "Science Translational Medicine",

issn = "1946-6234",

publisher = "American Association for the Advancement of Science",

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Gendron, TF, Chew, J, Stankowski, JN, Hayes, LR, Zhang, YJ, Prudencio, M, Carlomagno, Y, Daughrity, LM, Jansen-West, K, Perkerson, EA, O'Raw, A, Cook, C, Pregent, L, Belzil, V, van Blitterswijk, M, Tabassian, LJ, Lee, CW, Yue, M, Tong, JM, Song, YP, Castanedes-Casey, M, Rousseau, L, Phillips, V, Dickson, DW, Rademakers, R, Fryer, JD, Rush, BK, Pedraza, O, Caputo, AM, Desaro, P, Palmucci, C, Robertson, A, Heckman, MG, Diehl, NN, Wiggs, E, Tierney, M, Braun, L, Farren, J, Lacomis, D, Ladha, S, Fournier, CN, McCluskey, LF, Elman, LB, Toledo, JB, McBride, JD, Tiloca, C, Morelli, C, Poletti, B, Solca, F, Prelle, A, Wuu, J, Jockel-Balsarotti, J, Rigo, F, Ambrose, C, Datta, A, Yang, WX, Raitcheva, D, Antognetti, G, McCampbell, A, van Swieten, JC, Miller, BL, Boxer, AL, Brown, RH, Bowser, R, Miller, TM, Trojanowski, JQ, Grossman, M, Berry, JD, Hu, WT, Ratti, A, Traynor, BJ, Disney, MD, Benatar, M, Silani, V, Glass, JD, Floeter, MK, Rothstein, JD, Boylan, KB & Petrucelli, L 2017, 'Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis', Science Translational Medicine, vol. 9, no. 383, eaai7866. https://doi.org/10.1126/scitranslmed.aai7866

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T1 - Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis

AU - Gendron, TF

AU - Chew, J

AU - Stankowski, JN

AU - Hayes, LR

AU - Zhang, YJ

AU - Prudencio, M

AU - Carlomagno, Y

AU - Daughrity, LM

AU - Jansen-West, K

AU - Perkerson, EA

AU - O'Raw, A

AU - Cook, C

AU - Pregent, L

AU - Belzil, V

AU - van Blitterswijk, M

AU - Tabassian, LJ

AU - Lee, CW

AU - Yue, M

AU - Tong, JM

AU - Song, YP

AU - Castanedes-Casey, M

AU - Rousseau, L

AU - Phillips, V

AU - Dickson, DW

AU - Rademakers, R

AU - Fryer, JD

AU - Rush, BK

AU - Pedraza, O

AU - Caputo, AM

AU - Desaro, P

AU - Palmucci, C

AU - Robertson, A

AU - Heckman, MG

AU - Diehl, NN

AU - Wiggs, E

AU - Tierney, M

AU - Braun, L

AU - Farren, J

AU - Lacomis, D

AU - Ladha, S

AU - Fournier, CN

AU - McCluskey, LF

AU - Elman, LB

AU - Toledo, JB

AU - McBride, JD

AU - Tiloca, C

AU - Morelli, C

AU - Poletti, B

AU - Solca, F

AU - Prelle, A

AU - Wuu, J

AU - Jockel-Balsarotti, J

AU - Rigo, F

AU - Ambrose, C

AU - Datta, A

AU - Yang, WX

AU - Raitcheva, D

AU - Antognetti, G

AU - McCampbell, A

AU - van Swieten, J.C.

AU - Miller, BL

AU - Boxer, AL

AU - Brown, RH

AU - Bowser, R

AU - Miller, TM

AU - Trojanowski, JQ

AU - Grossman, M

AU - Berry, J D

AU - Hu, WT

AU - Ratti, A

AU - Traynor, BJ

AU - Disney, MD

AU - Benatar, M

AU - Silani, V

AU - Glass, JD

AU - Floeter, MK

AU - Rothstein, JD

AU - Boylan, KB

AU - Petrucelli, L

PY - 2017

Y1 - 2017

U2 - 10.1126/scitranslmed.aai7866

DO - 10.1126/scitranslmed.aai7866

M3 - Article

C2 - 28356511

SN - 1946-6234

VL - 9

JO - Science Translational Medicine

JF - Science Translational Medicine

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M1 - eaai7866

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