Polymorphism in CC-chemokine ligand 2 associated with tuberculosis in Zambia

Patricia Buijtels; Wendy Laureijssen - van de Sande; S Parkinson; PLC (Pieter) Petit; MAB van der Sande; D van Soolingen; Henri Verbrugh; Alex Belkum

Polymorphism in CC-chemokine ligand 2 associated with tuberculosis in Zambia

Patricia Buijtels, Wendy Laureijssen - van de Sande, S Parkinson, PLC (Pieter) Petit, MAB van der Sande, D van Soolingen, Henri Verbrugh, Alex Belkum

Medical Microbiology & Infectious Diseases

Research output: Contribution to journal › Article › Academic › peer-review

23 Citations (Scopus)

Abstract

Polymorphism in various genes that may influence susceptibility to tuberculosis (TB) was examined in 46 TB patients and 119 healthy tuberculin-positive controls In Zambia. The odds of having TB was 2.8-fold higher in carriers of the -2518 AG single-nucleotide polymorphism in the promoter region of the CC-chemokine ligand 2 than in those carrying the homozygous genotype AA (95%CI 1.3-5.5).

Original language	Undefined/Unknown
Pages (from-to)	1485-1488
Number of pages	4
Journal	International Journal of Tuberculosis and Lung Disease
Volume	12
Issue number	12
Publication status	Published - 2008

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Cite this

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title = "Polymorphism in CC-chemokine ligand 2 associated with tuberculosis in Zambia",

abstract = "Polymorphism in various genes that may influence susceptibility to tuberculosis (TB) was examined in 46 TB patients and 119 healthy tuberculin-positive controls In Zambia. The odds of having TB was 2.8-fold higher in carriers of the -2518 AG single-nucleotide polymorphism in the promoter region of the CC-chemokine ligand 2 than in those carrying the homozygous genotype AA (95%CI 1.3-5.5).",

author = "Patricia Buijtels and {Laureijssen - van de Sande}, Wendy and S Parkinson and Petit, {PLC (Pieter)} and {van der Sande}, MAB and {van Soolingen}, D and Henri Verbrugh and Alex Belkum",

year = "2008",

language = "Undefined/Unknown",

volume = "12",

pages = "1485--1488",

journal = "International Journal of Tuberculosis and Lung Disease",

issn = "1027-3719",

publisher = "International Union Against Tuberculosis and Lung Disease (The Union)",

number = "12",

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T1 - Polymorphism in CC-chemokine ligand 2 associated with tuberculosis in Zambia

AU - Buijtels, Patricia

AU - Laureijssen - van de Sande, Wendy

AU - Parkinson, S

AU - Petit, PLC (Pieter)

AU - van der Sande, MAB

AU - van Soolingen, D

AU - Verbrugh, Henri

AU - Belkum, Alex

PY - 2008

Y1 - 2008

N2 - Polymorphism in various genes that may influence susceptibility to tuberculosis (TB) was examined in 46 TB patients and 119 healthy tuberculin-positive controls In Zambia. The odds of having TB was 2.8-fold higher in carriers of the -2518 AG single-nucleotide polymorphism in the promoter region of the CC-chemokine ligand 2 than in those carrying the homozygous genotype AA (95%CI 1.3-5.5).

AB - Polymorphism in various genes that may influence susceptibility to tuberculosis (TB) was examined in 46 TB patients and 119 healthy tuberculin-positive controls In Zambia. The odds of having TB was 2.8-fold higher in carriers of the -2518 AG single-nucleotide polymorphism in the promoter region of the CC-chemokine ligand 2 than in those carrying the homozygous genotype AA (95%CI 1.3-5.5).

M3 - Article

SN - 1027-3719

VL - 12

SP - 1485

EP - 1488

JO - International Journal of Tuberculosis and Lung Disease

JF - International Journal of Tuberculosis and Lung Disease

IS - 12

ER -