Polymorphism in CC-chemokine ligand 2 associated with tuberculosis in Zambia

Patricia Buijtels, Wendy Laureijssen - van de Sande, S Parkinson, PLC (Pieter) Petit, MAB van der Sande, D van Soolingen, Henri Verbrugh, Alex Belkum

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Polymorphism in various genes that may influence susceptibility to tuberculosis (TB) was examined in 46 TB patients and 119 healthy tuberculin-positive controls In Zambia. The odds of having TB was 2.8-fold higher in carriers of the -2518 AG single-nucleotide polymorphism in the promoter region of the CC-chemokine ligand 2 than in those carrying the homozygous genotype AA (95%CI 1.3-5.5).
Original languageUndefined/Unknown
Pages (from-to)1485-1488
Number of pages4
JournalInternational Journal of Tuberculosis and Lung Disease
Issue number12
Publication statusPublished - 2008

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