Population pharmacokinetics of cyclosporine in kidney and heart transplant recipients and the influence of ethnicity and genetic polymorphisms in the MDR-1, CYP3A4 and CYP3A5 genes.

Dennis Hesselink; Teun Gelder; Ron van Schaik; Aggie Balk; IP van der Heiden; Th Dam; Marloes Werf; Willem Weimar; RAA Mathôt

doi:10.1016/j.clpt.2004.08.022

Population pharmacokinetics of cyclosporine in kidney and heart transplant recipients and the influence of ethnicity and genetic polymorphisms in the MDR-1, CYP3A4 and CYP3A5 genes.

Dennis Hesselink, Teun Gelder, Ron van Schaik, Aggie Balk, IP van der Heiden, Th Dam, Marloes Werf, Willem Weimar, RAA Mathôt

Research output: Contribution to journal › Article › Academic › peer-review

170 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	545-556
Number of pages	12
Journal	Clinical Pharmacology & Therapeutics
Volume	76
DOIs	https://doi.org/10.1016/j.clpt.2004.08.022
Publication status	Published - 2004

Research programs

EMC MM-04-39-05
EMC OR-01-25-01
EMC OR-01-34-01

Access to Document

10.1016/j.clpt.2004.08.022

http://hdl.handle.net/1765/57828

Cite this

Hesselink, D., Gelder, T., van Schaik, R., Balk, A., van der Heiden, IP., Dam, T., Werf, M., Weimar, W., & Mathôt, RAA. (2004). Population pharmacokinetics of cyclosporine in kidney and heart transplant recipients and the influence of ethnicity and genetic polymorphisms in the MDR-1, CYP3A4 and CYP3A5 genes. Clinical Pharmacology & Therapeutics, 76, 545-556. https://doi.org/10.1016/j.clpt.2004.08.022

@article{e8dd6274c2e54e92a6df9f2af2791ac4,

title = "Population pharmacokinetics of cyclosporine in kidney and heart transplant recipients and the influence of ethnicity and genetic polymorphisms in the MDR-1, CYP3A4 and CYP3A5 genes.",

author = "Dennis Hesselink and Teun Gelder and \{van Schaik\}, Ron and Aggie Balk and \{van der Heiden\}, IP and Th Dam and Marloes Werf and Willem Weimar and RAA Math{\^o}t",

year = "2004",

doi = "10.1016/j.clpt.2004.08.022",

language = "Undefined/Unknown",

volume = "76",

pages = "545--556",

journal = "Clinical Pharmacology \& Therapeutics",

issn = "0009-9236",

publisher = "Wiley-Blackwell",

}

Hesselink, D , Gelder, T , van Schaik, R, Balk, A, van der Heiden, IP, Dam, T, Werf, M, Weimar, W & Mathôt, RAA 2004, 'Population pharmacokinetics of cyclosporine in kidney and heart transplant recipients and the influence of ethnicity and genetic polymorphisms in the MDR-1, CYP3A4 and CYP3A5 genes.', Clinical Pharmacology & Therapeutics, vol. 76, pp. 545-556. https://doi.org/10.1016/j.clpt.2004.08.022

Population pharmacokinetics of cyclosporine in kidney and heart transplant recipients and the influence of ethnicity and genetic polymorphisms in the MDR-1, CYP3A4 and CYP3A5 genes. / Hesselink, Dennis ; Gelder, Teun ; van Schaik, Ron et al.
In: Clinical Pharmacology & Therapeutics, Vol. 76, 2004, p. 545-556.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Population pharmacokinetics of cyclosporine in kidney and heart transplant recipients and the influence of ethnicity and genetic polymorphisms in the MDR-1, CYP3A4 and CYP3A5 genes.

AU - Hesselink, Dennis

AU - Gelder, Teun

AU - van Schaik, Ron

AU - Balk, Aggie

AU - van der Heiden, IP

AU - Dam, Th

AU - Werf, Marloes

AU - Weimar, Willem

AU - Mathôt, RAA

PY - 2004

Y1 - 2004

U2 - 10.1016/j.clpt.2004.08.022

DO - 10.1016/j.clpt.2004.08.022

M3 - Article

C2 - 15592326

SN - 0009-9236

VL - 76

SP - 545

EP - 556

JO - Clinical Pharmacology & Therapeutics

JF - Clinical Pharmacology & Therapeutics

ER -