Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study

C Pottier; XL Zhou; RB Perkerson; M Baker; GD Jenkins; DJ Serie; R Ghidoni; L Benussi; G Binetti; AL de Munain; M Zulaica; F Moreno; I Le Ber; F Pasquier; D Hannequin; R Sanchez-Valle; A Antonell; A Llado; TM Parsons; NA Finch; EC Finger; CF Lippa; ED Huey; M Neumann; P Heutink; M Synofzik; C Wilke; RA Rissman; J Slawek; E Sitek; P Johannsen; JE Nielsen; YX Ren; M van Blitterswijk; M DeJesus-Hernandez; E Christopher; ME Murray; KF Bieniek; BM Evers; C Ferrari; S Rollinson; A Richardson; E Scarpini; GG Fumagalli; A Padovani; J Hardy; P Momeni; R Ferrari; F Frangipane; R Maletta; M Anfossi; M Gallo; L Petrucelli; E Suh; OL Lopez; Tse Wong; Jeroen van Rooij; Harro Seelaar; S Mead; RJ Caselli; EM Reiman; MN Sabbagh; M Kjolby; A Nykjaer; AM Karydas; AL Boxer; LT Grinberg; J Grafman; S Spina; A Oblak; MM Mesulam; S Weintraub; C Geula; JR Hodges; O Piguet; WS Brooks; DJ Irwin; JQ Trojanowski; EB Lee; KA Josephs; JE Parisi; N Ertekin-Taner; DS Knopman; B Nacmias; I Piaceri; S Bagnoli; S Sorbi; M Gearing; J Glass; TG Beach; SE Black; M Masellis; E Rogaeva; JP Vonsattel; LS Honig; J Kofler; AC Bruni; J Snowden; D Mann; S Pickering-Brown; J Diehl-Schmid; J Winkelmann; D Galimberti; C Graff; L Oijerstedt; C Troakes; S Al-Sarraj; C Cruchaga; NJ Cairns; JD Rohrer; GM Halliday; JB Kwok; J.C. van Swieten; CL White; B Ghetti; JR Murell; IRA Mackenzie; GYR Hsiung; B Borroni; G Rossi; F Tagliavini; ZK Wszolek; RC Petersen; EH Bigio; M Grossman; VM Van Deerlin; WW Seeley; BL Miller; NR Graff-Radford; BF Boeve; DW Dickson; JM Biernacka; R Rademakers

doi:10.1016/s1474-4422(18)30126-1

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study

C Pottier, XL Zhou, RB Perkerson, M Baker, GD Jenkins, DJ Serie, R Ghidoni, L Benussi, G Binetti, AL de Munain, M Zulaica, F Moreno, I Le Ber, F Pasquier, D Hannequin, R Sanchez-Valle, A Antonell, A Llado, TM Parsons, NA FinchEC Finger, CF Lippa, ED Huey, M Neumann, P Heutink, M Synofzik, C Wilke, RA Rissman, J Slawek, E Sitek, P Johannsen, JE Nielsen, YX Ren, M van Blitterswijk, M DeJesus-Hernandez, E Christopher, ME Murray, KF Bieniek, BM Evers, C Ferrari, S Rollinson, A Richardson, E Scarpini, GG Fumagalli, A Padovani, J Hardy, P Momeni, R Ferrari, F Frangipane, R Maletta, M Anfossi, M Gallo, L Petrucelli, E Suh, OL Lopez, Tse Wong, Jeroen van Rooij, Harro Seelaar, S Mead, RJ Caselli, EM Reiman, MN Sabbagh, M Kjolby, A Nykjaer, AM Karydas, AL Boxer, LT Grinberg, J Grafman, S Spina, A Oblak, MM Mesulam, S Weintraub, C Geula, JR Hodges, O Piguet, WS Brooks, DJ Irwin, JQ Trojanowski, EB Lee, KA Josephs, JE Parisi, N Ertekin-Taner, DS Knopman, B Nacmias, I Piaceri, S Bagnoli, S Sorbi, M Gearing, J Glass, TG Beach, SE Black, M Masellis, E Rogaeva, JP Vonsattel, LS Honig, J Kofler, AC Bruni, J Snowden, D Mann, S Pickering-Brown, J Diehl-Schmid, J Winkelmann, D Galimberti, C Graff, L Oijerstedt, C Troakes, S Al-Sarraj, C Cruchaga, NJ Cairns, JD Rohrer, GM Halliday, JB Kwok, J.C. van Swieten, CL White, B Ghetti, JR Murell, IRA Mackenzie, GYR Hsiung, B Borroni, G Rossi, F Tagliavini, ZK Wszolek, RC Petersen, EH Bigio, M Grossman, VM Van Deerlin, WW Seeley, BL Miller, NR Graff-Radford, BF Boeve, DW Dickson, JM Biernacka, R Rademakers

Research output: Contribution to journal › Article › Academic › peer-review

68 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	548-558
Number of pages	11
Journal	Lancet Neurology
Volume	17
Issue number	6
DOIs	https://doi.org/10.1016/s1474-4422(18)30126-1
Publication status	Published - 2018

Access to Document

10.1016/s1474-4422(18)30126-1

http://hdl.handle.net/1765/106230

Cite this

Pottier, C., Zhou, XL., Perkerson, RB., Baker, M., Jenkins, GD., Serie, DJ., Ghidoni, R., Benussi, L., Binetti, G., de Munain, AL., Zulaica, M., Moreno, F., Le Ber, I., Pasquier, F., Hannequin, D., Sanchez-Valle, R., Antonell, A., Llado, A., Parsons, TM., ... Rademakers, R. (2018). Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study. Lancet Neurology, 17(6), 548-558. https://doi.org/10.1016/s1474-4422(18)30126-1

@article{bc409b3eafbc40578c15a42eec73b742,

title = "Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study",

author = "C Pottier and XL Zhou and RB Perkerson and M Baker and GD Jenkins and DJ Serie and R Ghidoni and L Benussi and G Binetti and {de Munain}, AL and M Zulaica and F Moreno and {Le Ber}, I and F Pasquier and D Hannequin and R Sanchez-Valle and A Antonell and A Llado and TM Parsons and NA Finch and EC Finger and CF Lippa and ED Huey and M Neumann and P Heutink and M Synofzik and C Wilke and RA Rissman and J Slawek and E Sitek and P Johannsen and JE Nielsen and YX Ren and {van Blitterswijk}, M and M DeJesus-Hernandez and E Christopher and ME Murray and KF Bieniek and BM Evers and C Ferrari and S Rollinson and A Richardson and E Scarpini and GG Fumagalli and A Padovani and J Hardy and P Momeni and R Ferrari and F Frangipane and R Maletta and M Anfossi and M Gallo and L Petrucelli and E Suh and OL Lopez and Tse Wong and {van Rooij}, Jeroen and Harro Seelaar and S Mead and RJ Caselli and EM Reiman and MN Sabbagh and M Kjolby and A Nykjaer and AM Karydas and AL Boxer and LT Grinberg and J Grafman and S Spina and A Oblak and MM Mesulam and S Weintraub and C Geula and JR Hodges and O Piguet and WS Brooks and DJ Irwin and JQ Trojanowski and EB Lee and KA Josephs and JE Parisi and N Ertekin-Taner and DS Knopman and B Nacmias and I Piaceri and S Bagnoli and S Sorbi and M Gearing and J Glass and TG Beach and SE Black and M Masellis and E Rogaeva and JP Vonsattel and LS Honig and J Kofler and AC Bruni and J Snowden and D Mann and S Pickering-Brown and J Diehl-Schmid and J Winkelmann and D Galimberti and C Graff and L Oijerstedt and C Troakes and S Al-Sarraj and C Cruchaga and NJ Cairns and JD Rohrer and GM Halliday and JB Kwok and {van Swieten}, J.C. and CL White and B Ghetti and JR Murell and IRA Mackenzie and GYR Hsiung and B Borroni and G Rossi and F Tagliavini and ZK Wszolek and RC Petersen and EH Bigio and M Grossman and {Van Deerlin}, VM and WW Seeley and BL Miller and NR Graff-Radford and BF Boeve and DW Dickson and JM Biernacka and R Rademakers",

year = "2018",

doi = "10.1016/s1474-4422(18)30126-1",

language = "Undefined/Unknown",

volume = "17",

pages = "548--558",

journal = "The Lancet Neurology",

issn = "1474-4422",

publisher = "Lancet Publishing Group",

number = "6",

}

Pottier, C, Zhou, XL, Perkerson, RB, Baker, M, Jenkins, GD, Serie, DJ, Ghidoni, R, Benussi, L, Binetti, G, de Munain, AL, Zulaica, M, Moreno, F, Le Ber, I, Pasquier, F, Hannequin, D, Sanchez-Valle, R, Antonell, A, Llado, A, Parsons, TM, Finch, NA, Finger, EC, Lippa, CF, Huey, ED, Neumann, M, Heutink, P, Synofzik, M, Wilke, C, Rissman, RA, Slawek, J, Sitek, E, Johannsen, P, Nielsen, JE, Ren, YX, van Blitterswijk, M, DeJesus-Hernandez, M, Christopher, E, Murray, ME, Bieniek, KF, Evers, BM, Ferrari, C, Rollinson, S, Richardson, A, Scarpini, E, Fumagalli, GG, Padovani, A, Hardy, J, Momeni, P, Ferrari, R, Frangipane, F, Maletta, R, Anfossi, M, Gallo, M, Petrucelli, L, Suh, E, Lopez, OL, Wong, T, van Rooij, J , Seelaar, H, Mead, S, Caselli, RJ, Reiman, EM, Sabbagh, MN, Kjolby, M, Nykjaer, A, Karydas, AM, Boxer, AL, Grinberg, LT, Grafman, J, Spina, S, Oblak, A, Mesulam, MM, Weintraub, S, Geula, C, Hodges, JR, Piguet, O, Brooks, WS, Irwin, DJ, Trojanowski, JQ, Lee, EB, Josephs, KA, Parisi, JE, Ertekin-Taner, N, Knopman, DS, Nacmias, B, Piaceri, I, Bagnoli, S, Sorbi, S, Gearing, M, Glass, J, Beach, TG, Black, SE, Masellis, M, Rogaeva, E, Vonsattel, JP, Honig, LS, Kofler, J, Bruni, AC, Snowden, J, Mann, D, Pickering-Brown, S, Diehl-Schmid, J, Winkelmann, J, Galimberti, D, Graff, C, Oijerstedt, L, Troakes, C, Al-Sarraj, S, Cruchaga, C, Cairns, NJ, Rohrer, JD, Halliday, GM, Kwok, JB, van Swieten, JC, White, CL, Ghetti, B, Murell, JR, Mackenzie, IRA, Hsiung, GYR, Borroni, B, Rossi, G, Tagliavini, F, Wszolek, ZK, Petersen, RC, Bigio, EH, Grossman, M, Van Deerlin, VM, Seeley, WW, Miller, BL, Graff-Radford, NR, Boeve, BF, Dickson, DW, Biernacka, JM & Rademakers, R 2018, 'Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study', Lancet Neurology, vol. 17, no. 6, pp. 548-558. https://doi.org/10.1016/s1474-4422(18)30126-1

TY - JOUR

T1 - Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study

AU - Pottier, C

AU - Zhou, XL

AU - Perkerson, RB

AU - Baker, M

AU - Jenkins, GD

AU - Serie, DJ

AU - Ghidoni, R

AU - Benussi, L

AU - Binetti, G

AU - de Munain, AL

AU - Zulaica, M

AU - Moreno, F

AU - Le Ber, I

AU - Pasquier, F

AU - Hannequin, D

AU - Sanchez-Valle, R

AU - Antonell, A

AU - Llado, A

AU - Parsons, TM

AU - Finch, NA

AU - Finger, EC

AU - Lippa, CF

AU - Huey, ED

AU - Neumann, M

AU - Heutink, P

AU - Synofzik, M

AU - Wilke, C

AU - Rissman, RA

AU - Slawek, J

AU - Sitek, E

AU - Johannsen, P

AU - Nielsen, JE

AU - Ren, YX

AU - van Blitterswijk, M

AU - DeJesus-Hernandez, M

AU - Christopher, E

AU - Murray, ME

AU - Bieniek, KF

AU - Evers, BM

AU - Ferrari, C

AU - Rollinson, S

AU - Richardson, A

AU - Scarpini, E

AU - Fumagalli, GG

AU - Padovani, A

AU - Hardy, J

AU - Momeni, P

AU - Ferrari, R

AU - Frangipane, F

AU - Maletta, R

AU - Anfossi, M

AU - Gallo, M

AU - Petrucelli, L

AU - Suh, E

AU - Lopez, OL

AU - Wong, Tse

AU - van Rooij, Jeroen

AU - Seelaar, Harro

AU - Mead, S

AU - Caselli, RJ

AU - Reiman, EM

AU - Sabbagh, MN

AU - Kjolby, M

AU - Nykjaer, A

AU - Karydas, AM

AU - Boxer, AL

AU - Grinberg, LT

AU - Grafman, J

AU - Spina, S

AU - Oblak, A

AU - Mesulam, MM

AU - Weintraub, S

AU - Geula, C

AU - Hodges, JR

AU - Piguet, O

AU - Brooks, WS

AU - Irwin, DJ

AU - Trojanowski, JQ

AU - Lee, EB

AU - Josephs, KA

AU - Parisi, JE

AU - Ertekin-Taner, N

AU - Knopman, DS

AU - Nacmias, B

AU - Piaceri, I

AU - Bagnoli, S

AU - Sorbi, S

AU - Gearing, M

AU - Glass, J

AU - Beach, TG

AU - Black, SE

AU - Masellis, M

AU - Rogaeva, E

AU - Vonsattel, JP

AU - Honig, LS

AU - Kofler, J

AU - Bruni, AC

AU - Snowden, J

AU - Mann, D

AU - Pickering-Brown, S

AU - Diehl-Schmid, J

AU - Winkelmann, J

AU - Galimberti, D

AU - Graff, C

AU - Oijerstedt, L

AU - Troakes, C

AU - Al-Sarraj, S

AU - Cruchaga, C

AU - Cairns, NJ

AU - Rohrer, JD

AU - Halliday, GM

AU - Kwok, JB

AU - van Swieten, J.C.

AU - White, CL

AU - Ghetti, B

AU - Murell, JR

AU - Mackenzie, IRA

AU - Hsiung, GYR

AU - Borroni, B

AU - Rossi, G

AU - Tagliavini, F

AU - Wszolek, ZK

AU - Petersen, RC

AU - Bigio, EH

AU - Grossman, M

AU - Van Deerlin, VM

AU - Seeley, WW

AU - Miller, BL

AU - Graff-Radford, NR

AU - Boeve, BF

AU - Dickson, DW

AU - Biernacka, JM

AU - Rademakers, R

PY - 2018

Y1 - 2018

U2 - 10.1016/s1474-4422(18)30126-1

DO - 10.1016/s1474-4422(18)30126-1

M3 - Article

VL - 17

SP - 548

EP - 558

JO - The Lancet Neurology

JF - The Lancet Neurology

SN - 1474-4422

IS - 6

ER -