PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

J van Setten; JA Brody; Y Jamshidi; B R Swenson; AM Butler; H Campbell; FM Del Greco; DS Evans; Q Gibson; DF Gudbjartsson; KF Kerr; Bouwe Krijthe; LP Lyytikainen; C Muller; M Muller-Nurasyid; IM Nolte; S Padmanabhan; MD Ritchie; A Robino; AV Smith; M Steri; T Tanaka; A Teumer; S Trompet; S Ulivi; N Verweij; XY Yin; DO Arnar; FW Asselbergs; JS Bader; J Barnard; J Bis; S Blankenberg; E Boerwinkle; Y Bradford; BM Buckley; MK Chung; D Crawford; M den Hoed; JC Denny; AF Dominiczak; GB Ehret; Mark Eijgelsheim; PT Ellinor; SB Felix; OH Franco Duran; L Franke; TB Harris; H Holm; G Ilaria; A Iorio; M Kahonen; I Kolcic; Jan Kors; EG Lakatta; LJ Launer; HH Lin; H J Lin; RJF Loos; SA Lubitz; PW Macfarlane; JW Magnani; IM Leach; T Meitinger; BD Mitchell; T Munzel; G J Papanicolaou; A Peters; A Pfeufer; PP Pramstaller; OT Raitakari; JI Rotter; I Rudan; NJ Samani; D Schlessinger; Claudia Silva Aldana; MF Sinner; JD Smith; H Snieder; EZ Soliman; TD Spector; DJ Stott; K Strauch; KV Tarasov; U Thorsteinsdottir; André Uitterlinden; DR Van Wagoner; U Volker; H Volzke; M Waldenberger; HJ Westra; PS Wild; T Zeller; A Alonso; CL Avery; S Bandinelli; EJ Benjamin; F Cucca; M Dorr; L Ferrucci; P Gasparini; V Gudnason; C Hayward; SR Heckbert; AA Hicks; JW Jukema; S Kaab; T Lehtimaki; YM Liu; PB Munroe; A Parsa; O Polasek; BM Psaty; DM Roden; RB Schnabel; G Sinagra; K Stefansson; Bruno Stricker; P van der Harst; Cornelia Duijn; JF Wilson; SA Gharib; PIW de Bakker; A Isaacs; DE Arking; N Sotoodehnia

doi:10.1038/s41467-018-04766-9

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

J van Setten, JA Brody, Y Jamshidi, B R Swenson, AM Butler, H Campbell, FM Del Greco, DS Evans, Q Gibson, DF Gudbjartsson, KF Kerr, Bouwe Krijthe, LP Lyytikainen, C Muller, M Muller-Nurasyid, IM Nolte, S Padmanabhan, MD Ritchie, A Robino, AV SmithM Steri, T Tanaka, A Teumer, S Trompet, S Ulivi, N Verweij, XY Yin, DO Arnar, FW Asselbergs, JS Bader, J Barnard, J Bis, S Blankenberg, E Boerwinkle, Y Bradford, BM Buckley, MK Chung, D Crawford, M den Hoed, JC Denny, AF Dominiczak, GB Ehret, Mark Eijgelsheim, PT Ellinor, SB Felix, OH Franco Duran, L Franke, TB Harris, H Holm, G Ilaria, A Iorio, M Kahonen, I Kolcic, Jan Kors, EG Lakatta, LJ Launer, HH Lin, H J Lin, RJF Loos, SA Lubitz, PW Macfarlane, JW Magnani, IM Leach, T Meitinger, BD Mitchell, T Munzel, G J Papanicolaou, A Peters, A Pfeufer, PP Pramstaller, OT Raitakari, JI Rotter, I Rudan, NJ Samani, D Schlessinger, Claudia Silva Aldana, MF Sinner, JD Smith, H Snieder, EZ Soliman, TD Spector, DJ Stott, K Strauch, KV Tarasov, U Thorsteinsdottir, André Uitterlinden, DR Van Wagoner, U Volker, H Volzke, M Waldenberger, HJ Westra, PS Wild, T Zeller, A Alonso, CL Avery, S Bandinelli, EJ Benjamin, F Cucca, M Dorr, L Ferrucci, P Gasparini, V Gudnason, C Hayward, SR Heckbert, AA Hicks, JW Jukema, S Kaab, T Lehtimaki, YM Liu, PB Munroe, A Parsa, O Polasek, BM Psaty, DM Roden, RB Schnabel, G Sinagra, K Stefansson, Bruno Stricker, P van der Harst, Cornelia Duijn, JF Wilson, SA Gharib, PIW de Bakker, A Isaacs, DE Arking, N Sotoodehnia

Research output: Contribution to journal › Article › Academic › peer-review

48 Citations (Scopus)

7 Downloads (Pure)

Original language	Undefined/Unknown
Article number	2904
Journal	Nature Communications
Volume	9
DOIs	https://doi.org/10.1038/s41467-018-04766-9
Publication status	Published - 2018

Access to Document

10.1038/s41467-018-04766-9

REPUB_109635-OA.pdfFinal published version, 2.26 MB

http://hdl.handle.net/1765/109635

Cite this

van Setten, J., Brody, JA., Jamshidi, Y., Swenson, B. R., Butler, AM., Campbell, H., Del Greco, FM., Evans, DS., Gibson, Q., Gudbjartsson, DF., Kerr, KF., Krijthe, B., Lyytikainen, LP., Muller, C., Muller-Nurasyid, M., Nolte, IM., Padmanabhan, S., Ritchie, MD., Robino, A., ... Sotoodehnia, N. (2018). PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity. Nature Communications, 9, [2904]. https://doi.org/10.1038/s41467-018-04766-9

@article{40bf8e7e28b34d05ba584fa4d6d4231a,

title = "PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity",

author = "{van Setten}, J and JA Brody and Y Jamshidi and Swenson, {B R} and AM Butler and H Campbell and {Del Greco}, FM and DS Evans and Q Gibson and DF Gudbjartsson and KF Kerr and Bouwe Krijthe and LP Lyytikainen and C Muller and M Muller-Nurasyid and IM Nolte and S Padmanabhan and MD Ritchie and A Robino and AV Smith and M Steri and T Tanaka and A Teumer and S Trompet and S Ulivi and N Verweij and XY Yin and DO Arnar and FW Asselbergs and JS Bader and J Barnard and J Bis and S Blankenberg and E Boerwinkle and Y Bradford and BM Buckley and MK Chung and D Crawford and {den Hoed}, M and JC Denny and AF Dominiczak and GB Ehret and Mark Eijgelsheim and PT Ellinor and SB Felix and {Franco Duran}, OH and L Franke and TB Harris and H Holm and G Ilaria and A Iorio and M Kahonen and I Kolcic and Jan Kors and EG Lakatta and LJ Launer and HH Lin and Lin, {H J} and RJF Loos and SA Lubitz and PW Macfarlane and JW Magnani and IM Leach and T Meitinger and BD Mitchell and T Munzel and Papanicolaou, {G J} and A Peters and A Pfeufer and PP Pramstaller and OT Raitakari and JI Rotter and I Rudan and NJ Samani and D Schlessinger and {Silva Aldana}, Claudia and MF Sinner and JD Smith and H Snieder and EZ Soliman and TD Spector and DJ Stott and K Strauch and KV Tarasov and U Thorsteinsdottir and Andr{\'e} Uitterlinden and {Van Wagoner}, DR and U Volker and H Volzke and M Waldenberger and HJ Westra and PS Wild and T Zeller and A Alonso and CL Avery and S Bandinelli and EJ Benjamin and F Cucca and M Dorr and L Ferrucci and P Gasparini and V Gudnason and C Hayward and SR Heckbert and AA Hicks and JW Jukema and S Kaab and T Lehtimaki and YM Liu and PB Munroe and A Parsa and O Polasek and BM Psaty and DM Roden and RB Schnabel and G Sinagra and K Stefansson and Bruno Stricker and {van der Harst}, P and Cornelia Duijn and JF Wilson and SA Gharib and {de Bakker}, PIW and A Isaacs and DE Arking and N Sotoodehnia",

year = "2018",

doi = "10.1038/s41467-018-04766-9",

language = "Undefined/Unknown",

volume = "9",

journal = "Nature Communications",

issn = "2041-1723",

publisher = "Nature Publishing Group",

}

van Setten, J, Brody, JA, Jamshidi, Y, Swenson, BR, Butler, AM, Campbell, H, Del Greco, FM, Evans, DS, Gibson, Q, Gudbjartsson, DF, Kerr, KF, Krijthe, B, Lyytikainen, LP, Muller, C, Muller-Nurasyid, M, Nolte, IM, Padmanabhan, S, Ritchie, MD, Robino, A, Smith, AV, Steri, M, Tanaka, T, Teumer, A, Trompet, S, Ulivi, S, Verweij, N, Yin, XY, Arnar, DO, Asselbergs, FW, Bader, JS, Barnard, J, Bis, J, Blankenberg, S, Boerwinkle, E, Bradford, Y, Buckley, BM, Chung, MK, Crawford, D, den Hoed, M, Denny, JC, Dominiczak, AF, Ehret, GB, Eijgelsheim, M, Ellinor, PT, Felix, SB, Franco Duran, OH, Franke, L, Harris, TB, Holm, H, Ilaria, G, Iorio, A, Kahonen, M, Kolcic, I, Kors, J, Lakatta, EG, Launer, LJ, Lin, HH, Lin, HJ, Loos, RJF, Lubitz, SA, Macfarlane, PW, Magnani, JW, Leach, IM, Meitinger, T, Mitchell, BD, Munzel, T, Papanicolaou, GJ, Peters, A, Pfeufer, A, Pramstaller, PP, Raitakari, OT, Rotter, JI, Rudan, I, Samani, NJ, Schlessinger, D, Silva Aldana, C, Sinner, MF, Smith, JD, Snieder, H, Soliman, EZ, Spector, TD, Stott, DJ, Strauch, K, Tarasov, KV, Thorsteinsdottir, U, Uitterlinden, A, Van Wagoner, DR, Volker, U, Volzke, H, Waldenberger, M, Westra, HJ, Wild, PS, Zeller, T, Alonso, A, Avery, CL, Bandinelli, S, Benjamin, EJ, Cucca, F, Dorr, M, Ferrucci, L, Gasparini, P, Gudnason, V, Hayward, C, Heckbert, SR, Hicks, AA, Jukema, JW, Kaab, S, Lehtimaki, T, Liu, YM, Munroe, PB, Parsa, A, Polasek, O, Psaty, BM, Roden, DM, Schnabel, RB, Sinagra, G, Stefansson, K, Stricker, B, van der Harst, P, Duijn, C, Wilson, JF, Gharib, SA, de Bakker, PIW, Isaacs, A, Arking, DE & Sotoodehnia, N 2018, 'PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity', Nature Communications, vol. 9, 2904. https://doi.org/10.1038/s41467-018-04766-9

TY - JOUR

T1 - PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

AU - van Setten, J

AU - Brody, JA

AU - Jamshidi, Y

AU - Swenson, B R

AU - Butler, AM

AU - Campbell, H

AU - Del Greco, FM

AU - Evans, DS

AU - Gibson, Q

AU - Gudbjartsson, DF

AU - Kerr, KF

AU - Krijthe, Bouwe

AU - Lyytikainen, LP

AU - Muller, C

AU - Muller-Nurasyid, M

AU - Nolte, IM

AU - Padmanabhan, S

AU - Ritchie, MD

AU - Robino, A

AU - Smith, AV

AU - Steri, M

AU - Tanaka, T

AU - Teumer, A

AU - Trompet, S

AU - Ulivi, S

AU - Verweij, N

AU - Yin, XY

AU - Arnar, DO

AU - Asselbergs, FW

AU - Bader, JS

AU - Barnard, J

AU - Bis, J

AU - Blankenberg, S

AU - Boerwinkle, E

AU - Bradford, Y

AU - Buckley, BM

AU - Chung, MK

AU - Crawford, D

AU - den Hoed, M

AU - Denny, JC

AU - Dominiczak, AF

AU - Ehret, GB

AU - Eijgelsheim, Mark

AU - Ellinor, PT

AU - Felix, SB

AU - Franco Duran, OH

AU - Franke, L

AU - Harris, TB

AU - Holm, H

AU - Ilaria, G

AU - Iorio, A

AU - Kahonen, M

AU - Kolcic, I

AU - Kors, Jan

AU - Lakatta, EG

AU - Launer, LJ

AU - Lin, HH

AU - Lin, H J

AU - Loos, RJF

AU - Lubitz, SA

AU - Macfarlane, PW

AU - Magnani, JW

AU - Leach, IM

AU - Meitinger, T

AU - Mitchell, BD

AU - Munzel, T

AU - Papanicolaou, G J

AU - Peters, A

AU - Pfeufer, A

AU - Pramstaller, PP

AU - Raitakari, OT

AU - Rotter, JI

AU - Rudan, I

AU - Samani, NJ

AU - Schlessinger, D

AU - Silva Aldana, Claudia

AU - Sinner, MF

AU - Smith, JD

AU - Snieder, H

AU - Soliman, EZ

AU - Spector, TD

AU - Stott, DJ

AU - Strauch, K

AU - Tarasov, KV

AU - Thorsteinsdottir, U

AU - Uitterlinden, André

AU - Van Wagoner, DR

AU - Volker, U

AU - Volzke, H

AU - Waldenberger, M

AU - Westra, HJ

AU - Wild, PS

AU - Zeller, T

AU - Alonso, A

AU - Avery, CL

AU - Bandinelli, S

AU - Benjamin, EJ

AU - Cucca, F

AU - Dorr, M

AU - Ferrucci, L

AU - Gasparini, P

AU - Gudnason, V

AU - Hayward, C

AU - Heckbert, SR

AU - Hicks, AA

AU - Jukema, JW

AU - Kaab, S

AU - Lehtimaki, T

AU - Liu, YM

AU - Munroe, PB

AU - Parsa, A

AU - Polasek, O

AU - Psaty, BM

AU - Roden, DM

AU - Schnabel, RB

AU - Sinagra, G

AU - Stefansson, K

AU - Stricker, Bruno

AU - van der Harst, P

AU - Duijn, Cornelia

AU - Wilson, JF

AU - Gharib, SA

AU - de Bakker, PIW

AU - Isaacs, A

AU - Arking, DE

AU - Sotoodehnia, N

PY - 2018

Y1 - 2018

U2 - 10.1038/s41467-018-04766-9

DO - 10.1038/s41467-018-04766-9

M3 - Article

SN - 2041-1723

VL - 9

JO - Nature Communications

JF - Nature Communications

M1 - 2904

ER -