Preclinical studies to improve targeted radionuclide therapy for prostate cancer

Eline Ruigrok

Preclinical studies to improve targeted radionuclide therapy for prostate cancer

Eline Ruigrok

Radiology & Nuclear Medicine

Research output: Types of Thesis › Doctoral Thesis › Internal

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Abstract

The aim of the studies described in this thesis is to investigate methods to improve the therapeutic efficacy and safety of PCa targeting tracers by comparing and selecting the most optimal PCa targeting tracer, by exploring combined PCa-TRT with radiosensitizing strategies, by analyzing the effects of different therapeutic radionuclides, and lastly by identifying the acute, early and/or late radiotoxic effects caused by PCa-TRT. The results of these studies together have increased the general knowledge of PCa-TRT for PCa cancer, which will aid the development and improvement of the currently clinical available treatment options for PCa patients.

Original language	English
Awarding Institution	Erasmus University Rotterdam
Supervisors/Advisors	de Jong, Marion, Supervisor Verburg, Frederik Anton, Supervisor Nonnekens, Julie, Co-supervisor van Weerden, Wytske, Co-supervisor
Award date	21 Mar 2023
Place of Publication	Rotterdam
Print ISBNs	978-94-6419-725-9
Publication status	Published - 21 Mar 2023

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final dissertation Ruigrok, Eline Final published version, 18.2 MB

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title = "Preclinical studies to improve targeted radionuclide therapy for prostate cancer",

abstract = "The aim of the studies described in this thesis is to investigate methods to improve the therapeutic efficacy and safety of PCa targeting tracers by comparing and selecting the most optimal PCa targeting tracer, by exploring combined PCa-TRT with radiosensitizing strategies, by analyzing the effects of different therapeutic radionuclides, and lastly by identifying the acute, early and/or late radiotoxic effects caused by PCa-TRT. The results of these studies together have increased the general knowledge of PCa-TRT for PCa cancer, which will aid the development and improvement of the currently clinical available treatment options for PCa patients.",

author = "Eline Ruigrok",

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TY - BOOK

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AU - Ruigrok, Eline

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N2 - The aim of the studies described in this thesis is to investigate methods to improve the therapeutic efficacy and safety of PCa targeting tracers by comparing and selecting the most optimal PCa targeting tracer, by exploring combined PCa-TRT with radiosensitizing strategies, by analyzing the effects of different therapeutic radionuclides, and lastly by identifying the acute, early and/or late radiotoxic effects caused by PCa-TRT. The results of these studies together have increased the general knowledge of PCa-TRT for PCa cancer, which will aid the development and improvement of the currently clinical available treatment options for PCa patients.

AB - The aim of the studies described in this thesis is to investigate methods to improve the therapeutic efficacy and safety of PCa targeting tracers by comparing and selecting the most optimal PCa targeting tracer, by exploring combined PCa-TRT with radiosensitizing strategies, by analyzing the effects of different therapeutic radionuclides, and lastly by identifying the acute, early and/or late radiotoxic effects caused by PCa-TRT. The results of these studies together have increased the general knowledge of PCa-TRT for PCa cancer, which will aid the development and improvement of the currently clinical available treatment options for PCa patients.

M3 - Doctoral Thesis

SN - 978-94-6419-725-9

CY - Rotterdam

ER -

Preclinical studies to improve targeted radionuclide therapy for prostate cancer

Abstract

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