Predicting Patient-Specific Expansion of Abdominal Aortic Aneurysms

F Helderman, IJ Manoch, M Breeuwer, U Kose, Eric Boersma, Marc Sambeek, Peter Pattynama, Olaf Schouten, D Poldermans, W Wisselink, Ton van der Steen, R (Rob) Krams

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Objective: Local anatomy and the patient's risk profile independently affect the expansion rate of an abdominal aortic aneurysm. We describe a hybrid method that combines finite element modelling and statistical methods to predict patient-specific aneurysm expansion. Methods: The 3-D geometry of the aneurysm was imaged with computed tomography. We used finite element methods to calculate wall stress and aneurysm expansion. Expansion rate was adjusted by risk factors obtained from a database of 80 patients. Aneurysm diameters predicted with and without the risk profiles were compared with diameters measured with ultrasound for 11 patients. Results: For this specific group of patients, local anatomy contributed 62% and the risk profile 38% to the aneurysmal expansion rate. Predictions with risk profiles resulted in smaller root mean square errors than predictions without risk profiles (2.9 vs. 4.0 mm, p < 0.01). Conclusions: This hybrid approach predicted aneurysmal expansion for a period of 30 months with high accuracy. (C) 2010 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.
Original languageUndefined/Unknown
Pages (from-to)47-53
Number of pages7
JournalEuropean Journal of Vascular and Endovascular Surgery
Issue number1
Publication statusPublished - 2010

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