Prediction of the cumulated dose for external beam irradiation of prostate cancer patients with 3D-CRT technique

Marta Gizyńska*, Dorota Blatkiewicz, Beata Czyzew, Maciej Gałecki, Malgorzata Gil-Ulkowska, Pawel Kukołowicz

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Nowadays in radiotherapy, much effort is taken to minimize the irradiated volume and consequently minimize doses to healthy tissues. In our work, we tested the hypothesis that the mean dose distribution calculated from a few first fractions can serve as prediction of the cumulated dose distribution, representing the whole treatment. We made our tests for 25 prostate cancer patients treated with three orthogonal fields technique. We did a comparison of dose distribution calculated as a sum of dose distribution from each fraction with a dose distribution calculated with isocenter shifted for a mean setup error from a few first fractions. The cumulative dose distribution and predicted dose distributions are similar in terms of gamma (3 mm 3%) analysis, under condition that we know setup error from seven first fractions. We showed that the dose distribution calculated for the original plan with the isocenter shifted to the point, defined as the original isocenter corrected of the mean setup error estimated from the first seven fractions supports our hypothesis, i.e. can serve as a prediction for cumulative dose distribution.

Original languageEnglish
Pages (from-to)15-18
Number of pages4
JournalNukleonika
Volume61
Issue number1
DOIs
Publication statusPublished - 2016
Externally publishedYes

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