Premalignant epithelial disorders of the vulva: squamous vulvar intraepithelial neoplasia, vulvar Paget's disease and melanoma in situ

Annelinde Terlou, Leen Blok, Helmerhorst, M van Beurden

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30 Citations (Scopus)

Abstract

No standard screening programs exist to detect vulvar carcinoma or its precursor lesions, and therefore gynecologists, dermatologists and other healthcare providers in this field should be aware of the clinical features, behavior and management of the different existing premalignant vulvar lesions, squamous vulvar intraepithelial neoplasia (VIN), vulvar Paget's disease and melanoma in situ. In 2004, a new classification for squamous VIN was introduced by the International Society for the Study of Vulvar Disease, subdividing squamous VIN into the HPV-related usual type, and into differentiated type, which is associated with lichen sclerosus. This review describes the relevant aspects of squamous VIN, vulvar Paget's disease and melanoma in situ, its epidemiological characteristics, diagnosis, management and malignant potential.
Original languageUndefined/Unknown
Pages (from-to)741-U4
JournalActa Obstetricia et Gynecologica Scandinavica
Volume89
Issue number6
DOIs
Publication statusPublished - 2010

Research programs

  • EMC MM-03-52-02-A

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