Preoperative coronary angiography in vascular surgery patients with asymptomatic elevated high-sensitivity troponin T: a case series

Kristin Mol; Sanne Hoeks; Nicolas van Mieghem; Hence Verhagen; Eric Boersma; Robert jan Stolker; Felix van Lier

doi:10.1016/j.bja.2019.08.013

Preoperative coronary angiography in vascular surgery patients with asymptomatic elevated high-sensitivity troponin T: a case series

Kristin Mol, Sanne Hoeks, Nicolas van Mieghem, Hence Verhagen, Eric Boersma, Robert jan Stolker, Felix van Lier^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

4 Citations (Scopus)

40 Downloads (Pure)

Abstract

This case series presents 10 patients undergoing vascular surgery with asymptomatic elevated high-sensitivity troponin T concentrations, measured at outpatient clinic before surgery. Patients were included in the RAVE (Rotterdam Antiplatelet therapy in Vascular patiEnts) pilot study. All included patients underwent coronary angiography before surgery to identify significant obstructive coronary artery disease. We identified five out of 10 patients with high-grade stenosis and high-risk angiographic features of left main and/or proximal left anterior descending coronary artery disease. The study was terminated prematurely before any subject reached the study endpoint of 1 yr follow-up. This case series provides more insight into the meaning of preoperative troponin elevation and coronary angiographic features in vascular surgery patients. TRIAL REGISTRY NUMBER: NL5803.

Original language	English
Pages (from-to)	565-569
Number of pages	5
Journal	British Journal of Anaesthesia
Volume	123
Issue number	5
DOIs	https://doi.org/10.1016/j.bja.2019.08.013
Publication status	Published - Nov 2019

Bibliographical note

Funding:
Supported by ‘Stichting Lijf en Leven’. All researchers declare
full independency from the funders. Stichting Lijf en Leven
had no influence on study design, data analyses and interpretation, or development of this manuscript.

Research programs

EMC COEUR-09

Access to Document

10.1016/j.bja.2019.08.013Licence: Elsevier user license

Preoperative coronary angiography in vascular surgery patientsFinal published version, 332 KBLicence: Elsevier user license

http://hdl.handle.net/1765/119803

Cite this

@article{9a95e59735d04a62ab72fdff3feb04b4,

title = "Preoperative coronary angiography in vascular surgery patients with asymptomatic elevated high-sensitivity troponin T: a case series",

abstract = "This case series presents 10 patients undergoing vascular surgery with asymptomatic elevated high-sensitivity troponin T concentrations, measured at outpatient clinic before surgery. Patients were included in the RAVE (Rotterdam Antiplatelet therapy in Vascular patiEnts) pilot study. All included patients underwent coronary angiography before surgery to identify significant obstructive coronary artery disease. We identified five out of 10 patients with high-grade stenosis and high-risk angiographic features of left main and/or proximal left anterior descending coronary artery disease. The study was terminated prematurely before any subject reached the study endpoint of 1 yr follow-up. This case series provides more insight into the meaning of preoperative troponin elevation and coronary angiographic features in vascular surgery patients. TRIAL REGISTRY NUMBER: NL5803.",

author = "Kristin Mol and Sanne Hoeks and \{van Mieghem\}, Nicolas and Hence Verhagen and Eric Boersma and Stolker, \{Robert jan\} and \{van Lier\}, Felix",

note = "Funding: Supported by {\textquoteleft}Stichting Lijf en Leven{\textquoteright}. All researchers declare full independency from the funders. Stichting Lijf en Leven had no influence on study design, data analyses and interpretation, or development of this manuscript.",

year = "2019",

month = nov,

doi = "10.1016/j.bja.2019.08.013",

language = "English",

volume = "123",

pages = "565--569",

journal = "British Journal of Anaesthesia",

issn = "0007-0912",

publisher = "Elsevier Ltd.",

number = "5",

}

TY - JOUR

T1 - Preoperative coronary angiography in vascular surgery patients with asymptomatic elevated high-sensitivity troponin T

T2 - a case series

AU - Mol, Kristin

AU - Hoeks, Sanne

AU - van Mieghem, Nicolas

AU - Verhagen, Hence

AU - Boersma, Eric

AU - Stolker, Robert jan

AU - van Lier, Felix

N1 - Funding: Supported by ‘Stichting Lijf en Leven’. All researchers declare full independency from the funders. Stichting Lijf en Leven had no influence on study design, data analyses and interpretation, or development of this manuscript.

PY - 2019/11

Y1 - 2019/11

N2 - This case series presents 10 patients undergoing vascular surgery with asymptomatic elevated high-sensitivity troponin T concentrations, measured at outpatient clinic before surgery. Patients were included in the RAVE (Rotterdam Antiplatelet therapy in Vascular patiEnts) pilot study. All included patients underwent coronary angiography before surgery to identify significant obstructive coronary artery disease. We identified five out of 10 patients with high-grade stenosis and high-risk angiographic features of left main and/or proximal left anterior descending coronary artery disease. The study was terminated prematurely before any subject reached the study endpoint of 1 yr follow-up. This case series provides more insight into the meaning of preoperative troponin elevation and coronary angiographic features in vascular surgery patients. TRIAL REGISTRY NUMBER: NL5803.

AB - This case series presents 10 patients undergoing vascular surgery with asymptomatic elevated high-sensitivity troponin T concentrations, measured at outpatient clinic before surgery. Patients were included in the RAVE (Rotterdam Antiplatelet therapy in Vascular patiEnts) pilot study. All included patients underwent coronary angiography before surgery to identify significant obstructive coronary artery disease. We identified five out of 10 patients with high-grade stenosis and high-risk angiographic features of left main and/or proximal left anterior descending coronary artery disease. The study was terminated prematurely before any subject reached the study endpoint of 1 yr follow-up. This case series provides more insight into the meaning of preoperative troponin elevation and coronary angiographic features in vascular surgery patients. TRIAL REGISTRY NUMBER: NL5803.

U2 - 10.1016/j.bja.2019.08.013

DO - 10.1016/j.bja.2019.08.013

M3 - Article

SN - 0007-0912

VL - 123

SP - 565

EP - 569

JO - British Journal of Anaesthesia

JF - British Journal of Anaesthesia

IS - 5

ER -

Preoperative coronary angiography in vascular surgery patients with asymptomatic elevated high-sensitivity troponin T: a case series

Abstract

Bibliographical note

Research programs

Access to Document

Fingerprint

Cite this