Prevention of hepatic encephalopathy by administration of rifaximin and lactulose in patients with liver cirrhosis undergoing placement of a transjugular intrahepatic portosystemic shunt (TIPS): A multicentre randomised, double blind, placebo controlled trial (PEARL trial)

K de Wit; JJ Schaapman; F Nevens; J (Jos) Verbeek; Sandra Coenen; FJC Cuperus; M de Kramer; ET Tjwa; N Mostafavi; MG Dijkgraaf; OM van Delden; UHW Beuers; MJ Coenraad; RB Takkenberg

doi:10.1136/bmjgast-2020-000531

Prevention of hepatic encephalopathy by administration of rifaximin and lactulose in patients with liver cirrhosis undergoing placement of a transjugular intrahepatic portosystemic shunt (TIPS): A multicentre randomised, double blind, placebo controlled trial (PEARL trial)

K de Wit, JJ Schaapman, F Nevens, J (Jos) Verbeek, Sandra Coenen, FJC Cuperus, M de Kramer, ET Tjwa, N Mostafavi, MG Dijkgraaf, OM van Delden, UHW Beuers, MJ Coenraad, RB Takkenberg

Gastroenterology & Hepatology

Research output: Contribution to journal › Article › Academic › peer-review

3 Citations (Scopus)

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Original language	English
Article number	e000531
Journal	BMJ Open Gastroenterology
Volume	7
Issue number	1
DOIs	https://doi.org/10.1136/bmjgast-2020-000531
Publication status	Published - 2020

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de Wit, K., Schaapman, JJ., Nevens, F., Verbeek, J., Coenen, S., Cuperus, FJC., de Kramer, M., Tjwa, ET., Mostafavi, N., Dijkgraaf, MG., van Delden, OM., Beuers, UHW., Coenraad, MJ., & Takkenberg, RB. (2020). Prevention of hepatic encephalopathy by administration of rifaximin and lactulose in patients with liver cirrhosis undergoing placement of a transjugular intrahepatic portosystemic shunt (TIPS): A multicentre randomised, double blind, placebo controlled trial (PEARL trial). BMJ Open Gastroenterology, 7(1), [e000531]. https://doi.org/10.1136/bmjgast-2020-000531

de Wit, K ; Schaapman, JJ ; Nevens, F ; Verbeek, J (Jos) ; Coenen, Sandra ; Cuperus, FJC ; de Kramer, M ; Tjwa, ET ; Mostafavi, N ; Dijkgraaf, MG ; van Delden, OM ; Beuers, UHW ; Coenraad, MJ ; Takkenberg, RB. / Prevention of hepatic encephalopathy by administration of rifaximin and lactulose in patients with liver cirrhosis undergoing placement of a transjugular intrahepatic portosystemic shunt (TIPS): A multicentre randomised, double blind, placebo controlled trial (PEARL trial). In: BMJ Open Gastroenterology. 2020 ; Vol. 7, No. 1.

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title = "Prevention of hepatic encephalopathy by administration of rifaximin and lactulose in patients with liver cirrhosis undergoing placement of a transjugular intrahepatic portosystemic shunt (TIPS): A multicentre randomised, double blind, placebo controlled trial (PEARL trial)",

author = "{de Wit}, K and JJ Schaapman and F Nevens and Verbeek, {J (Jos)} and Sandra Coenen and FJC Cuperus and {de Kramer}, M and ET Tjwa and N Mostafavi and MG Dijkgraaf and {van Delden}, OM and UHW Beuers and MJ Coenraad and RB Takkenberg",

year = "2020",

doi = "10.1136/bmjgast-2020-000531",

language = "English",

volume = "7",

journal = "BMJ Open Gastroenterology",

issn = "2054-4774",

publisher = "BMJ Publishing Group",

number = "1",

}

de Wit, K, Schaapman, JJ, Nevens, F, Verbeek, J, Coenen, S, Cuperus, FJC, de Kramer, M, Tjwa, ET, Mostafavi, N, Dijkgraaf, MG, van Delden, OM, Beuers, UHW, Coenraad, MJ & Takkenberg, RB 2020, 'Prevention of hepatic encephalopathy by administration of rifaximin and lactulose in patients with liver cirrhosis undergoing placement of a transjugular intrahepatic portosystemic shunt (TIPS): A multicentre randomised, double blind, placebo controlled trial (PEARL trial)', BMJ Open Gastroenterology, vol. 7, no. 1, e000531. https://doi.org/10.1136/bmjgast-2020-000531

Prevention of hepatic encephalopathy by administration of rifaximin and lactulose in patients with liver cirrhosis undergoing placement of a transjugular intrahepatic portosystemic shunt (TIPS): A multicentre randomised, double blind, placebo controlled trial (PEARL trial). / de Wit, K; Schaapman, JJ; Nevens, F; Verbeek, J (Jos); Coenen, Sandra; Cuperus, FJC; de Kramer, M; Tjwa, ET; Mostafavi, N; Dijkgraaf, MG; van Delden, OM; Beuers, UHW; Coenraad, MJ; Takkenberg, RB.

In: BMJ Open Gastroenterology, Vol. 7, No. 1, e000531, 2020.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Prevention of hepatic encephalopathy by administration of rifaximin and lactulose in patients with liver cirrhosis undergoing placement of a transjugular intrahepatic portosystemic shunt (TIPS): A multicentre randomised, double blind, placebo controlled trial (PEARL trial)

AU - de Wit, K

AU - Schaapman, JJ

AU - Nevens, F

AU - Verbeek, J (Jos)

AU - Coenen, Sandra

AU - Cuperus, FJC

AU - de Kramer, M

AU - Tjwa, ET

AU - Mostafavi, N

AU - Dijkgraaf, MG

AU - van Delden, OM

AU - Beuers, UHW

AU - Coenraad, MJ

AU - Takkenberg, RB

PY - 2020

Y1 - 2020

U2 - 10.1136/bmjgast-2020-000531

DO - 10.1136/bmjgast-2020-000531

M3 - Article

VL - 7

JO - BMJ Open Gastroenterology

JF - BMJ Open Gastroenterology

SN - 2054-4774

IS - 1

M1 - e000531

ER -

de Wit K, Schaapman JJ, Nevens F, Verbeek J, Coenen S, Cuperus FJC et al. Prevention of hepatic encephalopathy by administration of rifaximin and lactulose in patients with liver cirrhosis undergoing placement of a transjugular intrahepatic portosystemic shunt (TIPS): A multicentre randomised, double blind, placebo controlled trial (PEARL trial). BMJ Open Gastroenterology. 2020;7(1). e000531. https://doi.org/10.1136/bmjgast-2020-000531