Prognosis of hospitalised older people with different levels of functioning: a prospective cohort study

KJE (Kirsten) Asmus, Paul Vreede, Linda Flinterman, Anna Petra Nieboer, TJEM Bakker, Gerard Borsboom, Johan Mackenbach, Ewout Steyerberg

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Abstract

Background: hospitalised older people are at risk for poor functioning after hospital discharge. We aimed to validate the predictive ability of the Identification Seniors At Risk-Hospitalized Patients (ISAR-HP) screening questionnaire to identify older patients at risk for functional dependence by comparing groups with different ISAR-HP scores on cognitive and physical functioning, mortality, health-related quality of life (HRQoL) and loneliness. Design: a longitudinal prospective cohort study. Setting: a 450-bed hospital in the Netherlands. Subjects: four hundred and sixty patients 65 years or older admitted between June 2010 and October 2010. Methods: participants were classified into five risk groups at hospital admission using the ISAR-HP. We interviewed patients at hospital admission and at 3 and 12 months after admission using validated questionnaires to score HRQoL, physical functioning, cognitive functioning and loneliness. Differences in survival were quantified by a concordance statistic (c). Results: cognitive functioning, physical functioning, loneliness and HRQoL differed significantly between groups during the 1-year follow-up after hospital admission (all comparisons P < 0.05), with high-risk groups having lower scores than low-risk groups for functioning and loneliness, although not always for HRQoL. The lowest risk group (ISAR-HP = 0) scored consistently higher on functioning and HRQoL than all other groups. Mortality differed significantly between groups (P < 0.001, c = 0.67) Conclusions: the ISAR-HP can readily distinguish well-functioning older patients from patients with low functioning and low HRQoL after hospital admission. The ISAR-HP may hence assist in selecting patients who may benefit from individually tailored reactivation treatment that is provided next to treatment of their medical condition.
Original languageUndefined/Unknown
Pages (from-to)803-809
Number of pages7
JournalAge and Ageing
Volume42
Issue number6
DOIs
Publication statusPublished - 2013

Research programs

  • EMC NIHES-05-63-02 Quality
  • EMC NIHES-02-65-01

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