Prognostic Histopathological and Molecular Markers on Prostate Cancer Needle-Biopsies: A Review

Marije Hoogland, Charlotte Kweldam, Arno van Leenders

Research output: Contribution to journalArticleAcademicpeer-review

35 Citations (Scopus)
3 Downloads (Pure)

Abstract

Prostate cancer is diverse in clinical presentation, histopathological tumor growth patterns, and survival. Therefore, individual assessment of a tumor's aggressive potential is crucial for clinical decision-making in men with prostate cancer. To date a large number of prognostic markers for prostate cancer have been described, most of them based on radical prostatectomy specimens. However, in order to affect clinical decision-making, validation of respective markers in pretreatment diagnostic needle-biopsies is essential. Here, we discuss established and promising histopathological and molecular parameters in diagnostic needle-biopsies.
Original languageUndefined/Unknown
JournalBioMed Research International
DOIs
Publication statusPublished - 2014

Cite this