Projections of costs and quality adjusted life years lost due to dementia from 2020 to 2050: A population-based microsimulation study

Chiara Brück*, Frank Wolters, Arfan Ikram, Inge de Kok

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)
58 Downloads (Pure)

Abstract

Introduction
Efficient healthcare planning requires reliable projections of the future increase in costs and quality-adjusted life years (QALYs) lost due to dementia.

Methods
We used the microsimulation model MISCAN-Dementia to simulate life histories and dementia occurrence using population-based Rotterdam Study data and nationwide birth cohort demographics. We estimated costs and QALYs lost in the Netherlands from 2020 to 2050, incorporating literature estimates of cost and utility for patients and caregivers by dementia severity and care setting.

Results
Societal costs and QALYs lost due to dementia are estimated to double between 2020 and 2050. Costs are incurred predominantly through institutional (34%), formal home (31%), and informal home care (20%). Lost QALYs are mostly due to shortened life expectancy (67%) and, to a lesser extent, quality of life with severe dementia (14%).

Discussion
To limit healthcare costs and quality of life losses due to dementia, interventions are needed that slow symptom progression and reduce care dependency.
Original languageEnglish
Pages (from-to)4532-4541
Number of pages10
JournalAlzheimers & Dementia
Volume19
Issue number10
Early online date14 Mar 2023
DOIs
Publication statusPublished - Oct 2023

Bibliographical note

Funding Information:
This work was supported by a VENI grant awarded to Inge M.C.M de Kok from the Dutch Research Council (Grant 016.Veni.198.020).

Publisher Copyright:
© 2023 The Authors. Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association.

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