Prospective assessment of fetal cardiac function with speckle tracking in healthy fetuses and recipient fetuses of twin-to-twin transfusion syndrome

Tim Van Mieghem; Sorin Giusca; Philip DeKoninck; Leonardo Gucciardo; Elisa Doné; An Hindryckx; Jan D'Hooge; Jan Deprest

doi:10.1016/j.echo.2009.12.024

Prospective assessment of fetal cardiac function with speckle tracking in healthy fetuses and recipient fetuses of twin-to-twin transfusion syndrome

Tim Van Mieghem
, Sorin Giusca
, Philip DeKoninck
, Leonardo Gucciardo
, Elisa Doné
, An Hindryckx
, Jan D'Hooge
, Jan Deprest

University Hospitals Leuven

Research output: Contribution to journal › Article › Academic › peer-review

93 Citations (Scopus)

Abstract

BACKGROUND: The aim of this study was to assess speckle tracking-derived fetal cardiac function in a normal population and in recipient fetuses of twin-to-twin transfusion syndrome (TTTS).

METHODS: A case-control study was conducted of 59 uncomplicated singleton pregnancies and 17 recipient fetuses of TTTS. Peak systolic strain, strain rate, velocity, and displacement were calculated, corrected for gestational age, and compared between patients with TTTS and controls.

RESULTS: The feasibility of speckle tracking was 83% in controls but only 61% in patients with TTTS. Myocardial velocity and displacement increased over gestation, and regional differences were present within each wall and between walls. Strain and strain rate were stable within each wall but were higher in the right ventricle than in the left ventricle and septum. Right ventricular strain was decreased in patients with TTTS compared with controls (0.75+/-0.34 vs 1.00+/-0.37 multiples of the median, P=.04).

CONCLUSION: The feasibility of speckle tracking is low when imaging conditions are challenging, but it can identify right ventricular failure in selected patients with TTTS.

Original language	English
Pages (from-to)	301-8
Number of pages	8
Journal	Journal of the American Society of Echocardiography
Volume	23
Issue number	3
DOIs	https://doi.org/10.1016/j.echo.2009.12.024
Publication status	Published - Mar 2010
Externally published	Yes

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10.1016/j.echo.2009.12.024

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Van Mieghem, T., Giusca, S., DeKoninck, P., Gucciardo, L., Doné, E., Hindryckx, A., D'Hooge, J., & Deprest, J. (2010). Prospective assessment of fetal cardiac function with speckle tracking in healthy fetuses and recipient fetuses of twin-to-twin transfusion syndrome. Journal of the American Society of Echocardiography, 23(3), 301-8. https://doi.org/10.1016/j.echo.2009.12.024

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title = "Prospective assessment of fetal cardiac function with speckle tracking in healthy fetuses and recipient fetuses of twin-to-twin transfusion syndrome",

abstract = "BACKGROUND: The aim of this study was to assess speckle tracking-derived fetal cardiac function in a normal population and in recipient fetuses of twin-to-twin transfusion syndrome (TTTS).METHODS: A case-control study was conducted of 59 uncomplicated singleton pregnancies and 17 recipient fetuses of TTTS. Peak systolic strain, strain rate, velocity, and displacement were calculated, corrected for gestational age, and compared between patients with TTTS and controls.RESULTS: The feasibility of speckle tracking was 83\% in controls but only 61\% in patients with TTTS. Myocardial velocity and displacement increased over gestation, and regional differences were present within each wall and between walls. Strain and strain rate were stable within each wall but were higher in the right ventricle than in the left ventricle and septum. Right ventricular strain was decreased in patients with TTTS compared with controls (0.75+/-0.34 vs 1.00+/-0.37 multiples of the median, P=.04).CONCLUSION: The feasibility of speckle tracking is low when imaging conditions are challenging, but it can identify right ventricular failure in selected patients with TTTS.",

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Van Mieghem, T, Giusca, S, DeKoninck, P, Gucciardo, L, Doné, E, Hindryckx, A, D'Hooge, J & Deprest, J 2010, 'Prospective assessment of fetal cardiac function with speckle tracking in healthy fetuses and recipient fetuses of twin-to-twin transfusion syndrome', Journal of the American Society of Echocardiography, vol. 23, no. 3, pp. 301-8. https://doi.org/10.1016/j.echo.2009.12.024

Prospective assessment of fetal cardiac function with speckle tracking in healthy fetuses and recipient fetuses of twin-to-twin transfusion syndrome. / Van Mieghem, Tim; Giusca, Sorin; DeKoninck, Philip et al.
In: Journal of the American Society of Echocardiography, Vol. 23, No. 3, 03.2010, p. 301-8.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Prospective assessment of fetal cardiac function with speckle tracking in healthy fetuses and recipient fetuses of twin-to-twin transfusion syndrome

AU - Van Mieghem, Tim

AU - Giusca, Sorin

AU - DeKoninck, Philip

AU - Gucciardo, Leonardo

AU - Doné, Elisa

AU - Hindryckx, An

AU - D'Hooge, Jan

AU - Deprest, Jan

PY - 2010/3

Y1 - 2010/3

N2 - BACKGROUND: The aim of this study was to assess speckle tracking-derived fetal cardiac function in a normal population and in recipient fetuses of twin-to-twin transfusion syndrome (TTTS).METHODS: A case-control study was conducted of 59 uncomplicated singleton pregnancies and 17 recipient fetuses of TTTS. Peak systolic strain, strain rate, velocity, and displacement were calculated, corrected for gestational age, and compared between patients with TTTS and controls.RESULTS: The feasibility of speckle tracking was 83% in controls but only 61% in patients with TTTS. Myocardial velocity and displacement increased over gestation, and regional differences were present within each wall and between walls. Strain and strain rate were stable within each wall but were higher in the right ventricle than in the left ventricle and septum. Right ventricular strain was decreased in patients with TTTS compared with controls (0.75+/-0.34 vs 1.00+/-0.37 multiples of the median, P=.04).CONCLUSION: The feasibility of speckle tracking is low when imaging conditions are challenging, but it can identify right ventricular failure in selected patients with TTTS.

AB - BACKGROUND: The aim of this study was to assess speckle tracking-derived fetal cardiac function in a normal population and in recipient fetuses of twin-to-twin transfusion syndrome (TTTS).METHODS: A case-control study was conducted of 59 uncomplicated singleton pregnancies and 17 recipient fetuses of TTTS. Peak systolic strain, strain rate, velocity, and displacement were calculated, corrected for gestational age, and compared between patients with TTTS and controls.RESULTS: The feasibility of speckle tracking was 83% in controls but only 61% in patients with TTTS. Myocardial velocity and displacement increased over gestation, and regional differences were present within each wall and between walls. Strain and strain rate were stable within each wall but were higher in the right ventricle than in the left ventricle and septum. Right ventricular strain was decreased in patients with TTTS compared with controls (0.75+/-0.34 vs 1.00+/-0.37 multiples of the median, P=.04).CONCLUSION: The feasibility of speckle tracking is low when imaging conditions are challenging, but it can identify right ventricular failure in selected patients with TTTS.

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DO - 10.1016/j.echo.2009.12.024

M3 - Article

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SN - 0894-7317

VL - 23

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EP - 308

JO - Journal of the American Society of Echocardiography

JF - Journal of the American Society of Echocardiography

IS - 3

ER -

Prospective assessment of fetal cardiac function with speckle tracking in healthy fetuses and recipient fetuses of twin-to-twin transfusion syndrome

Abstract

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