ProteoDisco: A flexible R approach to generate customized protein databases for extended search space of novel and variant proteins in proteogenomic studies

Wesley S. Van De Geer, Job Van Riet, Harmen J.G. Van De Werken*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

Summary: We present an R-based open-source software termed ProteoDisco that allows for flexible incorporation of genomic variants, fusion genes and (aberrant) transcriptomic variants from standardized formats into protein variant sequences. ProteoDisco allows for a flexible step-by-step workflow allowing for in-depth customization to suit a myriad of research approaches in the field of proteogenomics, on all organisms for which a reference genome and transcript annotations are available.

Original languageEnglish
Pages (from-to)1437-1439
Number of pages3
JournalBioinformatics
Volume38
Issue number5
DOIs
Publication statusPublished - 1 Mar 2022

Bibliographical note

Publisher Copyright:
© 2021 The Author(s) 2021. Published by Oxford University Press.

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