Protocol for the Examination of Specimens From Patients With Pheochromocytomas and Extra-Adrenal Paragangliomas

O Mete, AS Tischler, Ronald de Krijger, AM McNicol, G Eisenhofer, K Pacak, S Ezzat, SL Asa

Research output: Contribution to journalArticleAcademicpeer-review

39 Citations (Scopus)

Abstract

During the last decade there have been revolutionary breakthroughs in understanding the biology of pheochromocytomas and extra-adrenal paragangliomas. Discoveries of new susceptibility genes and genotype-phenotype correlations have led to the realization that appropriate patient care requires a complete integration of clinical, genetic, biochemical, imaging, and pathology findings. Clinical practice has in many cases not kept pace with the rate of discovery, underscoring a need for updated procedures for evaluation of patient specimens and reporting of data. We therefore propose a new synoptic reporting approach for pheochromocytomas and extra-adrenal paragangliomas that will provide clear and uniform information to pathologists and clinicians, in order to advance the diagnosis of these neoplasms and optimize patient care.
Original languageUndefined/Unknown
Pages (from-to)182-188
Number of pages7
JournalArchives of pathology
Volume138
Issue number2
DOIs
Publication statusPublished - 2014

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