Psychiatric Genomics

Evangelia Eirini Tsermpini; Martin Alda; George P. Patrinos

doi:10.1016/C2019-0-00030-1

Psychiatric Genomics

Evangelia Eirini Tsermpini, Martin Alda, George P. Patrinos

Pathology

Research output: Book/Report/Inaugural speech/Farewell speech › Book › Academic

Abstract

Psychiatric Genomics presents and synthesizes available knowledge in the field of psychiatric genomics, offering methodologies to advance new research and aid clinical translation. After providing an introduction to genomics and psychiatry, international experts discuss the genomic basis of schizophrenia, bipolar disorder, depression, personality disorders, anxiety disorders, addictions, eating disorders, and sleep disorders, among other disorders. In addition, recommendations for next steps in clinical implementation and drug discovery are discussed in-depth, with chapters dedicated to pharmacogenomics and antipsychotics, antidepressants and mood stabilizers, adverse drug reactions, implementation of pharmacogenomics in psychiatric clinics, and ethical issues. Finally, methods sections provide a solid grounding in research approaches and computational analytics, from using animal models in psychiatric genomics and accessing biobanks, to employing computational analysis, genome-wide association studies (GWAS), brain pathophysiology, and endophenotypes in psychiatric research.

Original language	English
Publisher	Elsevier Inc.
Number of pages	388
ISBN (Electronic)	9780128196021
ISBN (Print)	9780128214008
DOIs	https://doi.org/10.1016/C2019-0-00030-1
Publication status	Published - 1 Jan 2022

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© 2022 Elsevier Inc. All rights reserved.

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Psychiatric Genomics

Abstract

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