Pull vs. Wet: rendimiento diagnóstico y calidad de las muestras de las paaf guiadas por use en las masas sólidas del páncreas

Translated title of the contribution: Pull vs. Wet: Diagnostic performance and sample quality of eus-guided fna in solid lesions of pancreas

Cecilia Curvale*, Ignacio Málaga, Paloma Rojas Saunero, Viviana Tassi, Enrique Martins, Jer Hwang Hui

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

Differential diagnosis of pancreatic masses is challenging. The endoscopic ultrasound-guided fine-needle aspiration method with the highest diagnostic yield has not been esta-blished. It was realized a prospective, randomized, double-blind study of the endoscopic ultrasound-guided fine-needle aspiration in solid lesions of the pancreas to compare and evaluate diagnostic yield and aspirate quality between wet and pull technique. Forty-one patients were enrolled. The wet technique presented a sensitivity, a specificity, a positive and negative predictive value, and a diagnostic accuracy of 58.3%, 100%, 100%, 25% and 63.4%, respectively. In the capillary technique they were: 75%, 100%, 100%, 35.7% and 78.1%, respectively. Comparing the diagnostic yield between both techniques, there was no statistically significant difference (McNemar's test p = 0.388). Regarding the cellularity of the specimen, both in cytology and the cell block samples, no significant difference was observed between the techniques (p = 0.84 and 0.61, respectively). With res-pect to contaminating blood in the specimen, there was no difference in cytology samples (p = 0.89) and no difference in cell block samples (p = 0.08). The suitability of cytology samples for diagnosis was similar in both techniques (wet = 57.5% and capillary = 56.7%, p = 0.94) and there was no difference in cell block samples (wet = 75% and capillary = 66.1%, p = 0.38). In this study we did not observe differences in diagnostic yield or sample quality. Since both techniques are effective, we suggest the simultaneous and alternate use of both methods.

Translated title of the contributionPull vs. Wet: Diagnostic performance and sample quality of eus-guided fna in solid lesions of pancreas
Original languageSpanish
Pages (from-to)42-51
Number of pages10
JournalActa Gastroenterologica Latinoamericana
Volume51
Issue number1
DOIs
Publication statusPublished - 22 Mar 2021

Bibliographical note

Agradecimientos. Esta investigación contó con el apoyo financiero de la Sociedad Argentina de Gastroenterología a
través de su beca para la investigación en gastroenterología del 2017.

Publisher Copyright: © 2021, Sociedad Argentina de Gastroenterologia. All rights reserved.

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