Quality of life and societal costs in patients with dilated cardiomyopathy

I Wiethoff*, M Sikking, S Evers, A Gabrio, M Henkens, M Michels, J Verdonschot, S Heymans, M Hiligsmann

*Corresponding author for this work

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Abstract

Aims Dilated cardiomyopathy (DCM) is a major cause of heart failure impairing patient wellbeing and imposing a substantial economic burden on society, but respective data are missing. This study aims to measure the quality of life (QoL) and societal costs of DCM patients. Met hods a nd results A cross-sectional evaluation of QoL and societal costs of DCM patients was performed through the 5-level EuroQol and the Medical Consumption Questionnaire and Productivity Cost Questionnaire, respectively. QoL was translated into numerical values (i.e. utilities). Costs were measured from a Dutch societal perspective. Final costs were extrapolated to 1 year, reported in 2022 Euros, and compared between DCM severity according to NYHA classes. A total of 550 DCM patients from the Maastricht cardiomyopathy registry were included. Mean age was 61 years, and 34% were women. Overall utility was slightly lower for DCM patients than the population mean (0.840 vs. 0.869, P = 0.225). Among EQ-5D dimensions, DCM patients scored lowest in 'usual activities'. Total societal DCM costs were €14 843 per patient per year. Cost drivers were productivity losses ( €7037) and medical costs ( €4621). Patients with more symptomatic DCM (i.e. NYHA class III or IV) had significantly higher average DCM costs per year compared to less symptomatic DCM ( €31 099 vs. €11 446, P < 0.001) and significantly lower utilities (0.631 vs. 0.883, P < 0.001). Conclusion DCM is associated with high societal costs and reduced QoL, in particular with high DCM severity.

Original languageEnglish
Pages (from-to)334-344
Number of pages11
JournalEuropean heart journal. Quality of care & clinical outcomes
Volume10
Issue number4
Early online date14 Sept 2023
DOIs
Publication statusPublished - 1 Jun 2024

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© The Author(s) 2023.

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