TY - GEN
T1 - Quantifying calcification in the lumbar aorta on X-ray images
AU - Conrad-Hansen, Lars A.
AU - De Bruijne, Marleen
AU - Lauze, François
AU - Tankó, László B.
AU - Pettersen, Paola C.
AU - He, Qing
AU - Chen, Jianghong
AU - Christiansen, Claus
AU - Nielsen, Mads
PY - 2007
Y1 - 2007
N2 - In this paper we propose to use inpainting to estimate the severity of atherosclerotic plaques from X-ray projections. Inpainting allows to "remove" the plaque and estimate what the background image for an uncalcified aorta would have looked like. A measure of plaque severity can then be derived by subtracting the inpainting from the original image. In contrast to the current standard of categorical calcification scoring from X-rays, our method estimates both the size and the density of calcified areas and provides a continuous severity score, thus allowing for measurement of more subtle differences. We discuss a class of smooth inpainting methods, compare their ability to reconstruct the original images, and compare the inpainting based calcification score to the conventional categorical score in a longitudinal study on 49 patients addressing correlations of the calcification scores with hypertension, a known cardiovascular risk factor.
AB - In this paper we propose to use inpainting to estimate the severity of atherosclerotic plaques from X-ray projections. Inpainting allows to "remove" the plaque and estimate what the background image for an uncalcified aorta would have looked like. A measure of plaque severity can then be derived by subtracting the inpainting from the original image. In contrast to the current standard of categorical calcification scoring from X-rays, our method estimates both the size and the density of calcified areas and provides a continuous severity score, thus allowing for measurement of more subtle differences. We discuss a class of smooth inpainting methods, compare their ability to reconstruct the original images, and compare the inpainting based calcification score to the conventional categorical score in a longitudinal study on 49 patients addressing correlations of the calcification scores with hypertension, a known cardiovascular risk factor.
UR - http://www.scopus.com/inward/record.url?scp=79551689522&partnerID=8YFLogxK
U2 - 10.1007/978-3-540-75759-7_43
DO - 10.1007/978-3-540-75759-7_43
M3 - Conference proceeding
C2 - 18044588
AN - SCOPUS:79551689522
SN - 9783540757580
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 352
EP - 359
BT - Medical Image Computing and Computer-Assisted Intervention - MICCAI 2007 - 10th International Conference, Proceedings
T2 - 10th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2007
Y2 - 29 October 2007 through 2 November 2007
ER -