Radiotherapy dosimetry with ultrasound contrast agents

Research output: Types of ThesisDoctoral ThesisInternal

Abstract

Deviations during radiotherapy may induce excessive damage to healthy tissues, resulting in severe secondary effects. To overcome these deviations, we have investigated the combination of ultrasound contrast agents and ultrasound imaging as a novel approach for in vivo radiation dosimetry. The ultrasound contrast agents studied here are injectable particles, generally smaller than a red-blood-cell, with a gaseous (bubbles) or a liquid core (droplets). Our goal was to assess, in well-controlled in vitro environments, the effect of ionizing radiation on the acoustic response of these agents, as well as the ultrasound imaging sequences that would optimize the dosimetric performance of these agents.
Original languageEnglish
Awarding Institution
  • Erasmus University Rotterdam
Supervisors/Advisors
  • de Jong, Nico, Supervisor
  • van der Steen, Ton, Supervisor
  • Vos, Rik, Co-supervisor
Award date18 Jan 2023
Place of PublicationRotterdam
Print ISBNs978-94-6421-973-9
Publication statusPublished - 18 Jan 2023

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