Randomized Clinical Trial of Total Extraperitoneal Inguinal Hernioplasty vs Lichtenstein Repair A Long-term Follow-up Study

Hasan Eker, Hester Langeveld, Pieter Klitsie, M Riet, LPS (Laurents) Stassen, WF Weidema, Ewout Steyerberg, Johan Lange, HJ (Jaap) Bonjer, J (Hans) Jeekel

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Hypothesis: Mesh repair is generally preferred for surgical correction of inguinal hernia, although the merits of endoscopic techniques over open surgery are still debated. Herein, minimally invasive total extraperitoneal inguinal hernioplasty (TEP) was compared with Lichtenstein repair to determine if one is associated with less postoperative pain, hypoesthesia, and hernia recurrence. Design: Prospective multicenter randomized clinical trial. Setting: Academic research. Patients: Six hundred sixty patients were randomized to TEP or Lichtenstein repair. Main Outcome Measures: The primary outcome was postoperative pain. Secondary end points were hernia recurrence, operative complications, operating time, length of hospital stay, time to complete recovery, quality of life, chronic pain, and operative costs. Results: At 5 years after surgery, TEP was associated with less chronic pain (P=.004). Impairment of inguinal sensibility was less frequently seen after TEP vs Lichtenstein repair (1% vs 22%, P<.001). Operative complications were more frequent after TEP vs Lichtenstein repair (6% vs 2%, P<.001), while no difference was noted in length of hospital stay. After TEP, patients had faster time to return to daily activities (P<.002) and less absence from work (P=.001). Although operative costs were hig Conclusions: In the short term, TEP was associated with more operative complications, longer operating time, and higher operative costs; however, total costs were comparable for the 2 procedures. Chronic pain and impairment of inguinal sensibility were more frequent after Lichtenstein repair. Although overall hernia recurrence rates were comparable for both procedures, hernia recurrence rates among experienced surgeons were significantly lower after TEP. Patient satisfaction was also significant
Original languageUndefined/Unknown
Pages (from-to)256-260
Number of pages5
JournalArchives of Surgery
Issue number3
Publication statusPublished - 2012

Research programs

  • EMC NIHES-02-65-01
  • EMC ONWAR-01-94-01
  • EMC OR-02-47-12

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