TY - JOUR
T1 - Randomized study to assess the effect of thrombus aspiration on flow area in patients with ST-elevation myocardial infarction: an optical frequency domain imaging study-TROFI trial
AU - Onuma, Yoshinobu
AU - Thuesen, L
AU - van Geuns, Robert Jan
AU - van der Ent, M
AU - Desch, S
AU - Fajadet, J
AU - Christiansen, E
AU - Smits, P
AU - Holm, NR
AU - Regar, Evelyn
AU - van Mieghem, Nicolas
AU - Borovicanin, V
AU - Paunovic, D
AU - Senshu, K
AU - Es, Gerrit-anne
AU - Muramatsu, Takashi
AU - Lee, IS
AU - Schuler, G
AU - Zijlstra, Felix
AU - Garcia Garcia, Hector
AU - Serruys, PWJC (Patrick)
PY - 2013
Y1 - 2013
N2 - Aims Primary percutaneous coronary intervention (PPCI) with thrombectomy (TB) seems to reduce the thrombus burden, resulting in a larger flow area as measured with optical frequency domain imaging (OFDI). Methods and results In a multi-centre study, 141 patients with ST elevation myocardial infarction,12 h from onset were randomized to either PPCI with TB using an Eliminate catheter (TB: n = 71) or without TB (non-TB: n = 70), having operators blinded for the OFDI results. The primary endpoint was minimum flow area (MinFA) post-procedure assessed by OFDI, defined as: [stent area + incomplete stent apposition (ISA) area] - (intraluminal defect + tissue prolapse area). Sample size was based on the Conclusion PPCI with TB was associated with a similar flow area as well as stent area to PPCI without TB.
AB - Aims Primary percutaneous coronary intervention (PPCI) with thrombectomy (TB) seems to reduce the thrombus burden, resulting in a larger flow area as measured with optical frequency domain imaging (OFDI). Methods and results In a multi-centre study, 141 patients with ST elevation myocardial infarction,12 h from onset were randomized to either PPCI with TB using an Eliminate catheter (TB: n = 71) or without TB (non-TB: n = 70), having operators blinded for the OFDI results. The primary endpoint was minimum flow area (MinFA) post-procedure assessed by OFDI, defined as: [stent area + incomplete stent apposition (ISA) area] - (intraluminal defect + tissue prolapse area). Sample size was based on the Conclusion PPCI with TB was associated with a similar flow area as well as stent area to PPCI without TB.
U2 - 10.1093/eurheartj/ehs456
DO - 10.1093/eurheartj/ehs456
M3 - Article
C2 - 23396493
SN - 0195-668X
VL - 34
SP - 1050-1060b
JO - European Heart Journal
JF - European Heart Journal
IS - 14
ER -