Rapid exchange ultra-thin microcatheter using fibre-optic sensing technology for measurement of intracoronary fractional flow reserve

Roberto Diletti, Nicolas van Mieghem, Marco Valgimigli, Antonios Karanasos, Bert Everaert, Joost Daemen, Robert Jan van Geuns, Peter de Jaegere, Felix Zijlstra, Evelyn Regar

Research output: Contribution to journalArticleAcademicpeer-review

24 Citations (Scopus)


Aims: The present report describes a novel coronary fractional flow reserve (FFR) system which allows FFR assessment using a rapid exchange microcatheter (RXi). Methods and results: The RXi microcatheter is compatible with standard 0.014 '' coronary guidewires facilitating lesion negotiation and FFR assessment in a wide range of coronary anatomies. In case of serial lesions, a microcatheter would have the important advantage of allowing multiple pullbacks while maintaining wire access to the vessel. The RXi is a fibre-optic sensor technology-based device. This technology might allow reduction in signal drift. The RXi microcatheter's fibre-optic sensor is located 5 mm from the distal tip. The microcatheter profile at the sensor site is 0.027 '' x0.036 ''. The segment of the catheter which is intended to reside within the target lesion is proximal to the sensor and has dimensions decreased to 0.020 '' x0.025 ''; these dimensions are comparable to a 0.022 '' circular-shaped wire. Conclusions: The RXi microcatheter FFR system represents a novel technology that could allow easier lesion negotiation, maintaining guidewire position, facilitating pullbacks for assessment of serial lesions and simplifying the obtainment of post-intervention FFR measurements. The optical sensing technology could additionally result in less signal drift. Further investigations are required to evaluate the clinical value of this technology fully.
Original languageUndefined/Unknown
Pages (from-to)428-432
Number of pages5
Issue number4
Publication statusPublished - 2015

Research programs

  • EMC COEUR-09

Cite this