TY - JOUR
T1 - Rare thoracic cancers
T2 - a comprehensive overview of diagnosis and management of small cell lung cancer, malignant pleural mesothelioma and thymic epithelial tumours
AU - Dumoulin, Daphne W.
AU - Bironzo, Paolo
AU - Passiglia, Francesco
N1 - Publisher Copyright:
© The authors 2023.
PY - 2023/3/1
Y1 - 2023/3/1
N2 - Despite the progress in outcomes seen with immunotherapy in various malignancies, including nonsmall cell lung cancer, the benefits are less in small cell lung cancer, malignant pleural mesothelioma and thymic epithelial tumours. New effective treatment options are needed, guided via more in-depth insights into the pathophysiology of these rare malignancies. This review comprehensively presents an overview of the clinical presentation, diagnostic tools, staging systems, pathophysiology and treatment options for these rare thoracic cancers. In addition, opportunities for further improvement of therapies are discussed.
AB - Despite the progress in outcomes seen with immunotherapy in various malignancies, including nonsmall cell lung cancer, the benefits are less in small cell lung cancer, malignant pleural mesothelioma and thymic epithelial tumours. New effective treatment options are needed, guided via more in-depth insights into the pathophysiology of these rare malignancies. This review comprehensively presents an overview of the clinical presentation, diagnostic tools, staging systems, pathophysiology and treatment options for these rare thoracic cancers. In addition, opportunities for further improvement of therapies are discussed.
UR - http://www.scopus.com/inward/record.url?scp=85147723515&partnerID=8YFLogxK
U2 - 10.1183/16000617.0174-2022
DO - 10.1183/16000617.0174-2022
M3 - Article
C2 - 36754434
AN - SCOPUS:85147723515
SN - 0905-9180
VL - 32
JO - European Respiratory Review
JF - European Respiratory Review
IS - 167
M1 - 220174
ER -