Rare thoracic cancers: a comprehensive overview of diagnosis and management of small cell lung cancer, malignant pleural mesothelioma and thymic epithelial tumours

Daphne W. Dumoulin; Paolo Bironzo; Francesco Passiglia; Joachim Aerts

doi:10.1183/16000617.0174-2022

Rare thoracic cancers: a comprehensive overview of diagnosis and management of small cell lung cancer, malignant pleural mesothelioma and thymic epithelial tumours

Daphne W. Dumoulin^*
, Paolo Bironzo
, Francesco Passiglia
, Joachim Aerts

^*Corresponding author for this work

Pulmonary Medicine

University of Turin

Research output: Contribution to journal › Article › Academic › peer-review

12 Citations (Scopus)

71 Downloads (Pure)

Abstract

Despite the progress in outcomes seen with immunotherapy in various malignancies, including nonsmall cell lung cancer, the benefits are less in small cell lung cancer, malignant pleural mesothelioma and thymic epithelial tumours. New effective treatment options are needed, guided via more in-depth insights into the pathophysiology of these rare malignancies. This review comprehensively presents an overview of the clinical presentation, diagnostic tools, staging systems, pathophysiology and treatment options for these rare thoracic cancers. In addition, opportunities for further improvement of therapies are discussed.

Original language	English
Article number	220174
Journal	European Respiratory Review
Volume	32
Issue number	167
DOIs	https://doi.org/10.1183/16000617.0174-2022
Publication status	Published - 1 Mar 2023

Bibliographical note

Publisher Copyright: © The authors 2023.

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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Rare thoracic cancers a comprehensive overview of diagnosis and management of small cell lung cancer, malignant pleural mesothelioma and thymic epithelial tumoursFinal published version, 403 KBLicence: CC BY

Cite this

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Rare thoracic cancers: a comprehensive overview of diagnosis and management of small cell lung cancer, malignant pleural mesothelioma and thymic epithelial tumours. / Dumoulin, Daphne W.; Bironzo, Paolo; Passiglia, Francesco et al.
In: European Respiratory Review, Vol. 32, No. 167, 220174, 01.03.2023.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

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AU - Bironzo, Paolo

AU - Passiglia, Francesco

AU - Aerts, Joachim

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AB - Despite the progress in outcomes seen with immunotherapy in various malignancies, including nonsmall cell lung cancer, the benefits are less in small cell lung cancer, malignant pleural mesothelioma and thymic epithelial tumours. New effective treatment options are needed, guided via more in-depth insights into the pathophysiology of these rare malignancies. This review comprehensively presents an overview of the clinical presentation, diagnostic tools, staging systems, pathophysiology and treatment options for these rare thoracic cancers. In addition, opportunities for further improvement of therapies are discussed.

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Rare thoracic cancers: a comprehensive overview of diagnosis and management of small cell lung cancer, malignant pleural mesothelioma and thymic epithelial tumours

Abstract

Bibliographical note

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