TY - JOUR
T1 - Recovery and functional outcome after radial nerve palsy in adults with a humeral shaft fracture
T2 - a multicenter prospective case series
AU - Van Bergen, Saskia H.
AU - Van Lieshout, Esther M.M.
AU - Verhofstad, Michael H.J.
AU - Den Hartog, Dennis
AU - HUMMER Investigators
AU - Beetz, Ivo
AU - Bolhuis, Hugo W.
AU - Bos, P. Koen
AU - Bronkhorst, Maarten W.G.A.
AU - Bruijninckx, Milko M.M.
AU - De Haan, Jeroen
AU - Deenik, Axel R.
AU - Den Hoed, P. Ted
AU - Eversdijk, Martin G.
AU - Goslings, J. Carel
AU - Haverlag, Robert
AU - Heetveld, Martin J.
AU - Kerver, Albertus J.H.
AU - Kolkman, Karel A.
AU - Leenhouts, Peter A.
AU - Mahabier, Kiran C.
AU - Meylaerts, Sven A.G.
AU - Onstenk, Ron
AU - Poeze, Martijn
AU - Poolman, Rudolf W.
AU - Punt, Bas J.
AU - Ritchie, Ewan D.
AU - Roerdink, W. Herbert
AU - Roukema, Gert R.
AU - Sintenie, Jan Bernard
AU - Soesman, Nicolaj M.R.
AU - Ten Holder, Edgar J.T.
AU - Tuinebreijer, Wim E.
AU - Van der Elst, Maarten
AU - Van der Heijden, Frank H.W.M.
AU - Van der Linden, Frits M.
AU - der Zwaal, Peer Van
AU - Van Dijk, Jan P.
AU - Van Jonbergen, Hans Peter W.
AU - Verleisdonk, Egbert J.M.M.
AU - Vroemen, Jos P.A.M.
AU - Waleboer, Marco
AU - Wittich, Philippe
AU - Zuidema, Wietse P.
AU - Notenboom, Marije
N1 - Funding:
This project was supported by a grant from the Osteosynthesis and Trauma Care (OTC) Foundation (reference number 2013-DHEL). This organization was not involved in the study design, patient recruitment, data collection, data analysis, data interpretation, publication decisions, or in any aspect pertinent to this study.
Publisher Copyright:
© 2023 The Author(s)
PY - 2023/5
Y1 - 2023/5
N2 - Background: The consequences of radial nerve palsy associated with a humeral shaft fracture are unclear. The aim of this study was to examine the functional recovery of radial nerve palsy, at presentation or postoperatively, in patients with a humeral shaft fracture. Methods: Data from patients who participated in the HUMeral shaft fractures: measuring recovery after operative versus non-operative treatment (HUMMER) study, a multicenter prospective cohort study including adults with a closed humeral shaft fracture Arbeitsgemeinschaft für Osteosynthesefragen (AO) type 12A or 12B, and had radial nerve palsy at presentation or postoperatively, were extracted from the HUMMER database. The primary outcome measure was clinically assessed recovery of motor function of the radial nerve. Secondary outcomes consisted of treatment, functional outcome (Disabilities of the Arm, Shoulder, and Hand and Constant–Murley Score), pain level, quality of life (Short Form-36 and EuroQoL-5D-3L), activity resumption, and range of motion of the shoulder and elbow joint at 12 months after trauma. Results: Three of the 145 nonoperatively treated patients had radial nerve palsy at presentation. One recovered spontaneously and 1 after osteosynthesis. Despite multiple surgical interventions, the third patient had no recovery after entrapment between fracture fragments. Thirteen of the 245 operatively treated patients had radial nerve palsy at presentation; all recovered. Nine other patients had postoperative radial nerve palsy; 8 recovered. One had ongoing recovery at the last follow-up, after nerve release and suture repair due to entrapment under the plate. At 12 months, the functional outcome scores of all patients suggested full recovery regarding functional outcome, pain, quality of life, activity resumption, and range of motion. Conclusion: Radial nerve palsy in patients with a humeral shaft fracture at presentation or postoperatively functionally recovers in 94% and 89%, respectively.
AB - Background: The consequences of radial nerve palsy associated with a humeral shaft fracture are unclear. The aim of this study was to examine the functional recovery of radial nerve palsy, at presentation or postoperatively, in patients with a humeral shaft fracture. Methods: Data from patients who participated in the HUMeral shaft fractures: measuring recovery after operative versus non-operative treatment (HUMMER) study, a multicenter prospective cohort study including adults with a closed humeral shaft fracture Arbeitsgemeinschaft für Osteosynthesefragen (AO) type 12A or 12B, and had radial nerve palsy at presentation or postoperatively, were extracted from the HUMMER database. The primary outcome measure was clinically assessed recovery of motor function of the radial nerve. Secondary outcomes consisted of treatment, functional outcome (Disabilities of the Arm, Shoulder, and Hand and Constant–Murley Score), pain level, quality of life (Short Form-36 and EuroQoL-5D-3L), activity resumption, and range of motion of the shoulder and elbow joint at 12 months after trauma. Results: Three of the 145 nonoperatively treated patients had radial nerve palsy at presentation. One recovered spontaneously and 1 after osteosynthesis. Despite multiple surgical interventions, the third patient had no recovery after entrapment between fracture fragments. Thirteen of the 245 operatively treated patients had radial nerve palsy at presentation; all recovered. Nine other patients had postoperative radial nerve palsy; 8 recovered. One had ongoing recovery at the last follow-up, after nerve release and suture repair due to entrapment under the plate. At 12 months, the functional outcome scores of all patients suggested full recovery regarding functional outcome, pain, quality of life, activity resumption, and range of motion. Conclusion: Radial nerve palsy in patients with a humeral shaft fracture at presentation or postoperatively functionally recovers in 94% and 89%, respectively.
UR - http://www.scopus.com/inward/record.url?scp=85151493481&partnerID=8YFLogxK
U2 - 10.1016/j.jseint.2023.02.003
DO - 10.1016/j.jseint.2023.02.003
M3 - Article
C2 - 37266182
AN - SCOPUS:85151493481
SN - 2468-6026
VL - 7
SP - 516
EP - 522
JO - JSES International
JF - JSES International
IS - 3
ER -