Reference Values and Psychometric Properties of the Quality of Life After Traumatic Brain Injury: Overall Scale in Italy, the Netherlands, and the United Kingdom

Yi-Jhen Wu, Katrin Rauen, Marina Zeldovich, Daphne C. Voormolen, Amra Covic, Katrin Cunitz, Anne Marie Plass, Suzanne Polinder, Juanita A. Haagsma, Nicole von Steinbuechel*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Abstract

Objectives: The Quality of Life after Brain Injury-Overall Scale (QOLIBRI-OS) is a short screening instrument for assessing disease-specific health-related quality of life (HRQoL) after traumatic brain injury. To date, no reference values are available for the QOLIBRI-OS in general populations. Thus, this study aimed to establish reference values for the QOLIBRI-OS in general population samples from Italy, the Netherlands, and the United Kingdom. Methods: Data were collected using an online survey. The total sample comprised 11759 participants, consisting of 3549 Italian, 3564 Dutch, and 4646 British subjects. In this sample, 49% of the total sample did not report any health complaints, whereas 51% had at least 1 chronic health condition. Reference values were deduced for the QOLIBRI-OS for health-condition–related samples and total general population samples per country. To ensure the comparability of these values, measurement invariance was assessed using a multigroup confirmatory factor analysis. Covariates characterizing the reference values were selected with the help of regression analyses. Results: The confirmatory factor analysis confirmed that the QOLIBRI-OS scores measured the same traumatic brain injury–specific HRQoL construct across the 3 countries. Healthy individuals reported significantly higher HRQoL than individuals with at least 1 chronic health condition. Older age and higher education levels were significantly associated with higher HRQoL. Conclusions: Because the reference values displayed differences in terms of age and education level across the 3 countries, we recommend using country-specific reference values stratified by sociodemographic and health status in research and clinical practice.

Original languageEnglish
Pages (from-to)1319-1327
Number of pages9
JournalValue in Health
Volume24
Issue number9
Early online date13 Aug 2021
DOIs
Publication statusPublished - Sept 2021

Bibliographical note

Funding Information:
Funding/Support: CENTER-TBI was supported by the European Union's 7th Framework Programme (EC grant 602150). Additional funding was obtained from the Hannelore Kohl Stiftung (Germany), One Mind (USA), Integra LifeSciences Holdings Corporation (USA), and NeuroTrauma Sciences, LLC (USA).

Funding Information:
Funding/Support: CENTER-TBI was supported by the European Union’s 7th Framework Programme (EC grant 602150 ). Additional funding was obtained from the Hannelore Kohl Stiftung (Germany), One Mind (USA), Integra LifeSciences Holdings Corporation (USA), and NeuroTrauma Sciences , LLC (USA).

Publisher Copyright:
© 2021 ISPOR–The Professional Society for Health Economics and Outcomes Research

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